A year prior to diagnosis with T2 I developed an all over body rash which started as hives about 1 inch in size which grew bigger and bigger until they all connected and each of my arms and legs were one huge hive, very swollen and I can't even describe how itchy my whole body was. It lasted for 10 months, the hives never went away, as one diminished another would replace it. My body felt like I had thousands of ants crawling around under my skin and I literally became suicidal because I couldn't sleep, I couldn't rest because of the itching and my body was continually swelling up. My GP just kept putting me on antihistamines which did not do a thing to help. They didn't reduce the itch or the rash or the swelling. Eventually one morning I felt as if my face had taken on a life of its own, my eyes were barely visible, my lips were huge but more frighteningly, my airways were narrowing.
Luckily I had the presence of mind and the medical knowledge to dial 999 and say 'Anaphylaxis' to the operator. She kept me on the phone, told me to go and unlock my front door and to wait for the ambulance. They arrived literally in minutes and administered adrenalin to me in the ambulance and then took me to hospital. None of the doctors knew what had caused the rash and I was drip fed with antihistamines and steroids and eventually diagnosed with 'Chronic Idiopathic Urticaria' which basically means chronic hives of unknown cause. I left hospital still with the rash and the itching but at least my throat was now open.
Everything has a cause, whether we find it or not is another matter, but nothing happens without a cause. So I was unhappy with being given an Epipen and basically told to forget all about it, but to keep the Epipen on me just in case. I was also told I must NEVER be given ACE Inhibitors, Proton Pump Inhibitors or NSAIDS but was not told WHY.
My other worry was that my youngest son had had a similar episode a year before me for no apparent reason. His episode didn't last as long as mine but was severe enough for him to have to go to hospital. He was also given steroids and antihistamines but orally. He wasn't given an Epipen.
My rash has gone but my skin still itches but not as unbearably as back then. I know that diabetes sometimes brings skin problems and that it can also have an autoimmune aspect to it and I wonder if anyone else has had a similar experience or knows anything about the autoimmune aspect of diabetes? Any light anyone can shed on this would be much appreciated.

Just found this -
http://www.medicalnewstoday.com/articles/222766.php