Look AHEAD halted: Lifestyle management fails

[FergusCrawford]

Look AHEAD halted: Lifestyle management fails to reduce hard CV outcomes in diabetics
http://www.theheart.org/article/1458351 ... newsletter

[Indy51]

Would be interesting to know what diet they put the participants on. If it was the standard ADA diet, no wonder the study was stopped "for futility".

[borofergie]

NHS style High Carb / Low Calorie + Exercise Intervention fails, and study is abandoned after 11.5 years of a 13.5 year study.
http://www.nytimes.com/2012/10/20/healt ... html?_r=2&

A large federal study of whether diet and weight loss can prevent heart attacks and strokes in overweight and obese people with Type 2 diabetes has ended two years ahead of schedule because the intensive program did not help.

The study randomly assigned 5,145 overweight or obese people with Type 2 diabetes to either a rigorous diet and exercise regimen or to sessions in which they got general health information. The diet involved 1,200 to 1,500 calories a day for those weighing less than 250 pounds and 1,500 to 1,800 calories a day for those weighing more. The exercise program was at least 175 minutes a week of moderate exercise.

But 11 years after the study began, researchers concluded it was futile to continue — the two groups had nearly identical rates of heart attacks, strokes and cardiovascular deaths.

Here is the diet:

The recommended diet is based on guidelines of the ADA and National Cholesterol Education program [96,97] and includes a maximum of 30% of total calories from total fat, a maximum of 10% of total calories from saturated fat, and a minimum of 15% of total calories from protein.

http://perfecthealthdiet.com/2012/10/lo ... -crossing/

So it's a 55% carbohydrate diet, exactly the sort of thing advocated by the NHS and DUK.

There is some speculation among bloggers that the trail was halted because more people died in the intervention group than in the usual care group:
http://high-fat-nutrition.blogspot.co.u ... opped.html

However the massive omission, from the quick look I've managed, is of any intention to report the all cause mortality. It seems very likely to me that more people died in the intervention group than in the usual care group, but p was > 0.05.

Call me a cynic, but I think they stopped the trial because they could see where that p number was heading. Has anyone seen a body count from anywhere in the trial?

This is more excellent evidence against the idiotic (diabetic killing) dietary advice handed out by the NHS and DUK. It demonstrates the inefficacy of both low-calore + exercise and high-carb as a method of treating T2 diabetes.

Also, what might the outcome have been if the intervention group had been repeatedly bullied, harassed and indoctrinated to maintain a normoglycaemic, low grade ketogenic diet for 13.5 years? Say to an HbA1c of around 5%?

Ha ha ha bloody ha.

http://high-fat-nutrition.blogspot.co.u ... opped.html

Happy days indeed.

[borofergie]

Let's be clear about this:
High-Carb Diet = FAILED
Low-Calorie Diet = FAILED
Exercise = FAILED
therefore:
NHS + DUK Dietary Advice Coffin = NAILED

[Superchip]

Just spotted your reply fergie ! Brilliant !

Spot on, when will they learn ? and who paid for this confirmation of what most intelligent people already know and have done for donkeys years ?

Roy