I found I was reacting to the teflon in both the angled and "normal' 90 degree sets -- which meant I could barely get past 36hrs without the sets being so sore and itchy that I had to change them.... now on steel sets and WAY better -- even though they do sometimes still hit "funny bits" *and* i'm sensitive to the adhesive, I can at least keep them in for the full 48hrs and they don't leave itchy / raised sores when taken out... perhaps worth asking if you could try steel sets...?