PROBLEM WITH METFORMIN

[Smikey]

Can any one shed more light on the recent new findings on Metformin.
It seems that a new study has found that Metformin causes the heart metabolism in men to move in an undesirable direction.
The heart burns less sugar and more fats.
The Chronic burning of fat by the heart leads to detrimental changes in the heart muscle,which can lead to heart failure.
Instead of making the heart metabolism more normal in men, metformin alone made it worse, looking even more like a diabetic heart.
In women the it has the desired effect,lowering fat metabolism and increasing glucose uptake by the heart.
But they have also found that taking Viagra every few months halves the risk of men who have type 2 diabetes dying from heart problems.

 

[Enclave]

O so was my wife right to say I should have never been given this as I already have heart failure .. she is often right .. don't viagra ... so could not comment about that !

 

[JohnEGreen]

Is it this one?

Common diabetes drug metformin could cause thyroid and heart problems, experts warn


'
The study, published in Canadian Medical Association Journal, examined data on 74,300 patients who received metformin and sulfonylurea, another common diabetes drug, over a 25-year study period.
Of these people, 5,689 were being treated for an underactive thyroid, and 59,937 had normal thyroid function.
In the group with an underactive thyroid, there were 495 incidences of low thyroid-stimulating hormone (TSH) (119.7 per 1000) per year compared with 322 in the normal group (4.5 per 1000).
In patients with a treated underactive thyroid, metformin was associated with a 55 per cent increased risk of low TSH levels compared with treatment with sulfonylurea.
Metformin therapy did not appear to affect people with normal thyroid function.
Dr Laurent Azoulay at the Department of Oncology, McGill University, said: 'The results of this study confirmed that the use of metformin was associated with an increased risk of low TSH levels in patients with treated hypothyroidism.
'Given the relatively high incidence of low TSH levels in patients taking metformin, it is imperative that future studies assess the clinical consequences of this effect.' '

http://www.dailymail.co.uk/health/a...rt-disease-thyroid-problems-experts-warn.html

 

[Sid Bonkers]

The heart burns less sugar and more fats.

I wasnt even aware that the heart burned sugar or fat I always thought the heart was a just pump.

 

[JohnEGreen]

It is also a muscle and requires energy.