Hi, I haven't had a very good start to the New Year. I had been feeling anxious for about a week and this ended up in a sort of breakdown. I have seen the doctor and am on an anti-depressant (for anxiety). I am feeling better already but when I have finished the meds (I have enough for a month and am seeing the doctor in 3 weeks) I would like to take St Johns Wort as a natural way to ease anxiety. Does anyone know if it reacts badly with Metformin, Glibenclamide, Pioglitazone, Statin and an aspirin? I have asked a health food company but they aren't qualified to say. I imagine the GP won't know either as St Johns Wort is probably not on their list of recommended medicines. If anyone knows I would be glad to hear. Thanks.