A five-year prospective study of bone mineral density in men and women with diabetes: The Fremantle Diabetes Study

December 05, 2011

Emma J. Hamilton et al. Acta Diabetologica. doi: 10.1007/s00592-011-0324-7

The investigators examined longitudinally the effect of diabetes on bone structure and metabolism, by measuring bone mineral density and turnover markers in 26 type 1 and 27 type 2 diabetic patients without known osteoporosis.

Changes in biochemical markers suggested that, in type 1 men, there is ineffective bone formation associated with accelerated bone resorption and lower sex steroid bioavailability. The authors posit that their findings may have implications for the clinical management of young male adults with diabetes.

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