Research may highlight why so many diabetic women have caesarean births
The work, one of the few to examine why the ratio of diabetic women having caesarean births is so high, assessed over 100 biopsies of the uterus from pregnant diabetic and non-diabetic women.
It was shown that contractions in those with diabetes were not as strong as those without it, so the researchers examined potential differences in the changes in calcium within the muscle cells, a key element of uterine contractions. It was revealed that in diabetic women calcium levels was substantially lowered, and that channels in the cell membrane that are responsible for calcium entering the cells was also reduced.
In addition, uterus tissue in women with diabetes weren't reaching similar levels of contractility as for non-diabetic women when it was stimulated with the drug oxytocin, a common treatment for women facing a difficult birth, which could be why the amount of pregnancies in diabetic women that result in emergency caesareans is so high.
Researcher Sue Wray commented "Our work shows that calcium in inhibited from entering the muscle cells. This, together with evidence of reduced overall muscle mass, contributes to a poorly contracting uterus in women with diabetes."
Also related to this storyJoin the Community
Blood Glucose Monitoring System
Diabetes and Pregnancy
Study finds rise in dementia risk for diabetics
Colon cancer patients face worse prognosis if diabetic, says study
Health watchdog rejects use of eye drug Lucentis for diabetics
Very-low-calorie diet benefits for obese diabetics
Diabetics face amputation risk due to lack of health checks
Cabinet minister warned about effects of driving changes on diabetics
Acute kidney problems for diabetics in hospital can lead to chronic kidney disease
Diabetics with gum disease warned about blood sugar control
Diabetic youths needed to help research project
US diabetics recommended hepatitis B jab
Female diabetics more likely to develop breast cancer, according to study
Diabetics with lung cancer tend to live longer than non-diabetics
Brain volume affected by glycaemia in diabetics, according to study
Increasing good cholesterol could reduce heart problems for diabetics
More guidance needed on importance of oral health for diabetics
Asthma brings problems for diabetic kids
Study recommends against prescribing analogue insulin for diabetics
Diabetics face greater dementia risk, according to study
Warning about snacking on fatty foods for diabetics
Increase in obesity to blame for big rise in diabetic mortality rate
New type of anti-diabetic compound found
Diabetic men linked with cancer risk
Diabetic drivers could be banned by EU rule change
Diabetics face different risks of cardiovascular disease
Cancer drug could cause heart problems in diabetic older women