A new study has revealed a new molecular map that could explain the link between cancer and diabetes. It is hoped the map will offer a better understanding of the cancer risk that people suffering from type 2 diabetes face.
The research, carried out at Lund University in Sweden and published in the journal Human Molecular Genetics, uncovered a map of molecules that showed some of the reasons behind why people with diabetes have an increased likelihood of developing some types of cancer.
The team found that because there are long and complex phases for the development of type 2 diabetes, this provides more time for genes that are risky to the potential for cancer, called TCF and p53, to become prominent.
The two genes combine during the onset of diabetes, with TCF helping to defend against cell death and p53 preventing excessive cell division, a process that increases cancer risk. It is known that the risk variant of TCF is comparatively common, as 25 per cent of the general population carry it, while this rises to 31 per cent for diabetes patients.
Yuedan Zhou, lead author on the study, commented "We have worked with the most well-known risk gene for type 2 diabetes ' a variant of the TCF gene ' and have studied its function in the beta cells."
Molecular map that shows link between cancer and diabetes
Mon, 21 Nov 2011
Your comments may be moderated. Please report any spam, illegal, offensive or libellous posts.
Also related to this storyDiabetes Products
Diabetes Online Community
Type 2 Diabetes
Low Carb Diet
Diabetes in India
Diabetes and colon cancer link established
Female diabetics more likely to develop breast cancer, according to study
Diabetics with lung cancer tend to live longer than non-diabetics
Colon cancer risk increased by diabetes, says study
UK has bad record of treating pancreatic cancer says charity
Diabetic men linked with cancer risk
Cancer drug could cause heart problems in diabetic older women
Diabetes drug dapagliflozin could increase risk of cancer, says report
Actos suspended in France due to cancer risk
Ibuprofen to help fight cancer
People with diabetes at greater risk of cancer, according to report
Diabetes has negative effect on breast cancer patients
New study on link between prostate cancer and diabetes
Research into diabetes drug metformin as potential cancer treatment
Men with diabetes at greater risk of developing colon cancer
Diabetes drugs could help combat lung cancer
Diabetes and cancer research receives grant for small molecule study
Link found between diabetes drug Actos and bladder cancer
Diabetes drug can reduce lung cancer for smokers
Diabetes may reduce risk of prostate cancer
Diabetes causes greater risk of cancer for women
Diabetic medicines may increase risk of skewed results in cancer screenings
Study into cancer risk of type 2 diabetes
People with type 2 diabetes face increased risk of cancer
Diabetes patients face greater risk of colon cancer