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Kidney Impairment and its effect on Diabetics and Hypertension

Published by weiyeongtan in the blog weiyeongtan's blog. Views: 1007

About 2 or 3 years ago, My creatinine level was higher than normal and the last 6 months was about 172 around end July , About then I was having a back pain and was admitted to a hospital. While I was hospitalized diagnosed with kidney stone and possible an urinary track infection and was treated with "strong" antibiotics, My creatinine level then was about 195. When my blood pressure drop and I was put into close monitoring for a few days. When the creatinine level was down to about 165, the hospital blasted the stone with a stent inserted. I was discharged and when back to work on early August,, was again struck with low blood pressure and was admitted again. This time, the hospital review my medication dosage downward on both my diabetics and hypertension drugs. I relate this in my follow up with my heart specialists last week. From what he mentioned, it is probably due to my reduced kidney function. He mentioned that when the kidney function is reduced, the diabetic/hypertension drugs tends to stay longer in the blood and when the original dosage would have created "hypso" that affect the glucose and heart that cause the low blood pressure. That was probably why the medication for diabetics and hypertension are reduced.

I would like to know whether the kidney impairment will cause a chain effect on my diabetes and hypertension. I would like some opinion on how to deal with such kidney impairment, which currently is controlled using KETOSTERIL.

My latest (before review) medication dosage are
1 clopidogrel 75mg Tab (PLAVIX) 1TAB dly
2 carvedilol 6.25mg Tab (DILATREND) 2 TAB b/d (before review 25mg 1 TAB b/d)
3 felodipine ER 2.5mg Tab (PLENDIL) 1 TAB om (before review 5 mg 1 TAB om)
4 ezetimibe 10mg + simvastatin 40mg Tab (VYTORIN 10/40)
5 insulin glargine 300 unit/3ml lnj (LANTUS) 14 UNIT dly ((before review 36 UNIT dly)
6 gliclazide MR 60mg tab (DIAMICRON MR)1 TAB dly
7 sitagliptin 100mg Tab (JANUVIA) 0.5 TAB dly (before review I TAB dly)
8 isoleucine . 67 mg, leucine 101 mg, phenylalanine 68 mg, valine 86 mg, methionine 59 mg, L-lysine 105 mg,
L-threonine 53 mg, L-tryptophan 23 mg, L-histidine 38 mg, l-tyrosine 30 mg, nitrogen 36 mg (KETOSTERIL) 2 TAB b/d (before review Nil)
9 losartan 50mg + hydrochlorothiazide 12.5mg Tab (HYZAAR) Take off (before review 1 TAB dly)
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