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I was happy to find this site. I have been taking metformin for several years. I have always had back pain but it usually goes away with pain killer until more recently I have been suffering with lower back pain to no avail. The pain is Sharpe and debilitating. I of to lie still on the floor to get relief that sometimes is short lived while other times it lingered for days. Saw a neurologist and joint specialists and no relief unless I take opioids tramadol. The pain is horrific and to learn that metformin might be the culprit is shocking. Not one of the doctors mentioned that my back pain may an affiliation to metformin. I just want to thank you all for sharing this information.