Gliclazide 80mg v 30mg slow release

Icequeen55

Member
Messages
9
Type of diabetes
Treatment type
Tablets (oral)
Diabetes nurse put me on 80mg Gliclazide last Friday. Blood sugar dropped like a stone and I had a hypo on first day. Went to see GP yesterday for something else (been feeling dizzy and headachy turns out I have labyrinthitis just to add to my week of woes) mentioned the hypo and he's switched me to the 30mg slow release. My question is around whether the 30mg can cause hypos, I'm trying to reduce my carbs as through diet so just wondered if a hypo was a possibility?
 

13lizanne

Expert
Messages
8,262
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Dislikes
The Gym, + unkindness and rudeness
I was on 1x 40g gliclazide daily for a few weeks but when I started LCHF and my BG levels started to drop I stopped them ( round about 3.9 - 4.5 after exercise) I don't think they made much of a difference to me but we are all different and the only way that you'll know for sure is by trying out the new dosage and testing your levels frequently. Good luck!
 

MarcoRiveira

Well-Known Member
Messages
105
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Diamicron MR (Modified Release/Extended Release gliclazide) 30mg is comparable to 80mg standard gliclazide. I don't know how that can be, but it's in the product sheet of Diamicron MR

I take it myself once daily (half of 60mg tab), and 500mg Metformin 2x a day, and so far have had no hypo. Never tried standard gliclazide.

I'm not on LCHF, more like Medium Carbs, and my pre-dinner readings (8 hours after lunch) are 4.8 to 5.2 these days. The info below may help.

From the fact sheet -> https://www.medicines.org.uk/emc/medicine/4638

"This treatment should be prescribed only if the patient is likely to have a regular food intake (including breakfast). It is important to have a regular carbohydrate intake due to the increased risk of hypoglycaemia if a meal is taken late, if an inadequate amount of food is consumed or if the food is low in carbohydrate. Hypoglycaemia is more likely to occur during low-calorie diets, following prolonged or strenuous exercise, alcohol intake or if a combination of hypoglycaemic agents is being used."

Here, they also compare 30mg MR vs 80mg standard:
http://www.servier.ca/sites/default/files/webform/Products/EN-DIAMICRON-MR-PI.pdf
 
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Icequeen55

Member
Messages
9
Type of diabetes
Treatment type
Tablets (oral)
Thank you for this, very helpful. I have some visual disorganise, blurred vision mainly so im guessing it's the reduced blood sugar. Hopefully this will resolve itself.
 

MarcoRiveira

Well-Known Member
Messages
105
Type of diabetes
Type 2
Treatment type
Tablets (oral)
The first time my doctor prescribed my meds, Metformin and Diamicron MR, he told me I'll get blurred vision, and that I did not have to worry, as it will come back.

It has come back alright, same not better, after about 3 months from starting the meds.

I do hope yours goes back to what it was too, or even better.
 

Teresa9584

Member
Messages
14
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Dislikes
Vigorous exercise and chillies!
Diabetes nurse put me on 80mg Gliclazide last Friday. Blood sugar dropped like a stone and I had a hypo on first day. Went to see GP yesterday for something else (been feeling dizzy and headachy turns out I have labyrinthitis just to add to my week of woes) mentioned the hypo and he's switched me to the 30mg slow release. My question is around whether the 30mg can cause hypos, I'm trying to reduce my carbs as through diet so just wondered if a hypo was a possibility?
Hi. I too have labyrinthitis as well as type 2 diabetes. I ended up seeing a specialist at the local hospital and she gave me some great exercises to help with my balance. I've attached below and if you choose to try these I hope they help as much as they helped me. Try to stay positive as this can be a really difficult time. x

Vestibular Rehabilitation Exercises

Do 3 times a day, 10 times each exercise. Do them sitting safely and be careful afterwards

  1. Turn your head left and right slowly with eyes open.
  2. Turn your head left and right slowly with eyes closed.
  3. Move your head up and down slowly with eyed open.
  4. Move your head up and down slowly with eyed closed.
  5. Move your eyes left and right keeping your eyes still.
  6. Move your eyes up and down keeping your eyes still.
  7. VOR Exercise

    Look at your thumb in front of you at arms length (or a stationary target)
    Gently turn your head left and right keeping your eyes focused on your thumb.
    Don’t turn your head too far and don’t move your thumb.

    You may feel a little worse with your balance to start with – this is normal and
    will get easier with practice!