Hi Masna, I'm on 500mcg Metformin and 150 levothyroxine a day, originally prescribed 1000mcg Metformin but gave me dreadful stomach cramps and the rest so dropped back down. I don't find that they interact badly in any other way but I'm sure there are others on here who can tell you much more and that understand the science far better than I do.
Was warned at the beginning that hypothyroidism would make it very difficult to lose excess weight/control blood sugar and so convinced myself there was nothing I could really do about it but have been doing v low carb high fat for last 11weeks, lost almost 2 1/2 stone so far and just been informed by GP that my blood results have shown 'spectacular' improvement. Hoping they may take me off Metformin when I go see them this week.
Has your GP discussed dietary control with you first ?