People who believe that weight loss can only come about with a calorie deficit are making a number of incorrect assumptions about thermodynamics and the calorie theory. To go into just one of the errors here, by wrongly interpreting the first law of thermodynamics and therefore wrongly ignoring the second law, it is concluded that “a calorie is a calorie”.
As regards the second aspect of entropy in a human – energy used up in making useable energy – Eric Jequier, who works in the Institute of Physiology, University of Lausanne, Switzerland found that the thermic effect of nutrients (thermogenesis) is approximately 6-8% for carbohydrate, 2-3% for fat and 25-30% for protein.
http://www.zoeharcombe.com/2012/05/...t-is-the-official-advice-for-diabetics/#_edn1 I.e. approximately 6-8% of the calories consumed in the form of carbohydrate are used up in digesting the carbohydrate and turning it into fuel available to be used by the body. In contrast, 25-30% of the calories consumed in the form of protein are used up in digesting the protein and turning it into fuel available to be used by the body. This also makes intuitive sense; carbohydrates are relatively easy for the body to turn into energy (indeed they start being digested, and turned into glucose, with salivary enzymes, as soon as we start chewing). Protein needs to be broken down into amino acids, which is a far more complex process.
In lay terms is that protein can have a substantial ‘calorie advantage’ over carbs, simply because the body uses up far more calories in making protein available to the body as energy than it does in making carbs available as energy.
Fat/protein can be used for Basal Metabolic Rate (BMR) needs. Carbs can’t – they can only be used for energy. Hence we can virtually eat our BMR calories ‘for free’ – the body can use fat/protein/vitamins and minerals for everything from cell repair to building bone density to fighting infection. The body can only use carbs for energy. So we can eat 1,200 calories of carbs (thinking that we will lose weight) and, in fact, we will need to exercise to ‘burn up’ these calories. They are pretty useless to the body for any of its BMR needs. This is one of many reasons as to why calorie counters can apparently eat so little and still not lose weight and why the UK, as a whole, is overfed and undernourished – fat and sick.