Thanks
@tim2000s - it explains very well
The system I read about a while ago only used a TBR, which I didn't like the sound of. I'd want a faster solution if I was high.
The limit isn't really whether you use a TBR or a Microbolus. It's that the insulin is too slow, and the CGMs update every five minutes. What you're trying to balance is safety versus effectiveness.
For example, my dexcom sensor lost signal overnight (one of the issues with these systems, whoever makes them). It re-established connection at about 4.40am, it detected my glucose level at 13.8 and took action by delivering a temp basal of around 3.95U/hr, then 3.18U/hr which persisted for 15 mins, giving about 1u. It then provided slightly higher TBR for the next hour or so. The key aim is to drop you safely without you going Hypo, knowing what the insulin action curve looks like and what your insulin sensitivity is. The result was that I was back down in single figures in just over an hour.
The difference between 1U at 4.40 and 1U over fifteen minutes after 4.40 is actually quite limited in effects, in terms of rate of drop, but until you've run with one of these systems, you don't realise how little that 15 mins makes a difference. That's what I mean by needing faster insulins. What you also have to take into account is the max that will be delivered in one hit.
In the open source systems, Using the TBR model, we set a new TBR every five minutes, on the basis that in the worst case, the TBR will last for 30 mins and only deliver as much insulin as we can handle with fast carbs. The upper limit is controlled by the user, but shouldn't be set higher than the previous statement.
Likewise, in the microbolus model, there will be a maximum bolus that can be applied safely, and a max IOB that the system won't exceed in order to allow recovery in the event of something going amiss. Realistically, a microbolus model is going to operate in a way that is not too dissimilar to that of the TBR approach, in that you are more likely to have multiple smaller microboluses over a time period rather than one big one when higher, simply because it's a safer way to deliver the insulin and to monitor the outcome of the reaction.
Interestingly, the open source systems tell you what IOB looks like, including basals and boluses. From what I've heard about the Medtronic 670G it doesn't tell you this information when it lowers basal, so you don't have a full view on what your real IOB is.