Fiasp Insulin when is it available?

[TheBigNewt]

The first synthetic was Humulin by Lilly. That is identical to human human insulin molecule. They take animal insulin and knock off a couple of atoms I think. Humulog is Humulin with a slight change in the molecule to increase the onset of action. I don't know what Novorapid consists of.

 

[iHs]

I think a change is as good as a rest

 

[steve_p6]

The trials have shown no reduction in needed insulin, just faster and much faster action. The interesting change is HDV, which I expect to see in the next 18 months or so. It may well reduce the insulin requirements: http://www.diabettech.com/diabetes/...-be-hepatocyte-delivered-vesicle-for-insulin/

Novo have something in pipeline but only phase 1.

PI406 (NN1406)
Type 1 and 2 diabetes. Phase 1.
A liver-preferential mealtime insulin analogue.

 

[tim2000s]

I seem to recall that the work Diasome originally did with HDV was alongside Eli Lilly....

 

[steve_p6]

Pip codes
Fiasp®

(insulin aspart) PIP Code
SmPC
Fiasp®

FlexTouch® 403-9905 PIL
Fiasp®

Penfill® 403-9913 PIL
Fiasp®

vial 403-9897 PIL

 

[kzlorenz]

Hi guys I have just learnt that Fiasp is going to be commercialised in the same FlexTouch pen as Tresiba is!
I find this a terrible idea since even if one uses two pens of different colour it'll be easier to make a mistake and switch the two!

Has anyone any news on the matter ?

 

[tim2000s]

I've spoken to the South East London formulary today to find out about FIAsp. The process is that a consultant has to submit a request to any formulary and it then goes through a process that can take "up to three months" for the formulary to approve it.

SE London doesn't yet have a submission, but I'm told one is going in, so we may see it on the NHS in May/June time.

I'm going to see if I can convince someone to give me a private prescription for it as this doesn't seem to require NHS formulary sign off...

 

[Sideburnt]

I spoke to my GP on Friday 17th March and they didn’t have it as available. The prescription PIP codes are available on the Novo Nordisk site. http://www.novonordisk.co.uk/patients/diabetes/our-products.html

I’m going to give it until the end of the month and try again.

 

[LizLola]

I have it, and have been using it for two weeks. I emailed my DSN, who had a meeting with my Consultant, they okayed it, I phoned the GP, he wrote a paper prescription as it wasn't on his formulary, and my pharmacy got it in. Took a week all in.

It is miraculous after meals. I was warned not to take it more than two minutes before a meal. I ignored that after two days for my am dose - the reason I wanted it was to bring down my after breakfast high that was out of control. Now i do a correction and 1/3 of my breakfast dose on waking, get washed and then do the rest of my breakfast dose just before eating and my after breakfast blood sugar has been about 7.

I went on a four and a half hour walk with my dog and that would normally have entailed a LOT of glucose - but I never went under 4.5 and ended on 7.5, only needed one and half bottles of glucojuice (15g each) and didn't go high OR low after. (I'm on a pump, Medtronic, and CGM so can check every few minutes.)

BUT - and there is a but, the vitamin B or one of the excipients seems to be very irritant. I have had to change my cannula every 48 hours (normally every 3 days) and even so, it leaves a small pink lump under my skin.

Apart from that - miracle insulin, yes, it's just like being normal. Brings highs down very quickly.

 

[maria030660]

i want to move to Fiasp as Novorapid doesnt seem to kick in on time, plus since this year my insulin intake has doubled!

 

[LizLola]

It won't help with your doses. You need exactly the same as it IS Novorapid, just with different excipients to make it work faster.

 

[Sideburnt]

I've been using FIASP for a couple of weeks now, my chemist phoned the distributor and organised the issue of it as it hadn't hit the distribution database at that point. I rang my GP who issued the prescription (He's also a T1, very useful). It;s been great on the whole. Doses are exactly the same but I see action much sooner, the most difference is for corrective bolus shots that I would normally not see any activity or reduction for around an hour or more. These are now starting to come down after 20-25 mins and much quicker than I was used to with Apidra. Normal food boluses are kicking in at around the same time which is good to see as I digest at around the 15 minute mark for most food types so the spike is not as pronounced by quite a margin.

 

[smag3]

All sounds wonderful. Asked my diabetic nurse if I could have some and apparently York do not have it on their formulary so NO is the answer. Another lottery it would seem. Very very annoyed.

 

[LizLola]

smag3 - It wasn't on my hospital's formulary, either, but they okayed it and my GP wrote a paper prescription for me to go round pharmacies and find where it WAS available. Luckily my pharmacy in our village searched and found it for me. Don't take no for an answer - get the go-ahead and then phone your surgery, get a prescription and go hunt. Even if you have to go into another health authority territory.

 

[smag3]

smag3 - It wasn't on my hospital's formulary, either, but they okayed it and my GP wrote a paper prescription for me to go round pharmacies and find where it WAS available. Luckily my pharmacy in our village searched and found it for me. Don't take no for an answer - get the go-ahead and then phone your surgery, get a prescription and go hunt. Even if you have to go into another health authority territory.

Thank you. Will try that.

 

[dazwalshe]

I asked about Fiasp when I had my annual consultation at the hospital (April 23rd) - they had no idea it was available, said they would look into it for me. Monday, I receive a prescription in the post from the hospital for Fiasp flextouch ! handed in to the chemist Monday - collected yesterday - injecting today... so seems as though its pretty much out there and available now!!

 

[tim2000s]

I asked about Fiasp when I had my annual consultation at the hospital (April 23rd) - they had no idea it was available, said they would look into it for me. Monday, I receive a prescription in the post from the hospital for Fiasp flextouch ! handed in to the chemist Monday - collected yesterday - injecting today... so seems as though its pretty much out there and available now!!

Yup - it's been available for over a month!

 

[maria030660]

In Ireland where I live it won't be available till end of this year

 

[CJOtter]

Picked up my first vial this afternoon and filled a reservoir this evening. I am in SE London too and had to push my GP to prescribe it. They haven't put it on repeat yet "in case you don't like it better". They were concerned about monitoring it. That annoyed me as they don't monitor my pump at all! It must be in the formulary by now because the prescription was sent electronically to my pharmacy. If you're really cheeky you could ask your GP to change the script to generic Insulin Aspart and then ask the pharmacy to issue Fiasp...

 

[dazwalshe]

I've been on it for a month and a half now... and it is fabulous stuff. No more planning have before eating.. . Jabbing half hour before 10 mins after.. .. just bang 2 mins before.. works almost straightaway every time... combined with the freestyle libre.... flying high... hba1c down from 74 to 56 in 2 months... on course for 54 when I have blood test next week.... I can't praise it all highly enough....