Video from Thiamine Researchers

[goji]

This video is short and interesting on the deficiency in thiamine that is found in diabetics of both types.

http://www.youtube.com/watch?v=UNRaFjdeuZk

 

[catherinecherub]

Thanks for that goji.
As this was May 2008 I have looked for updates from Warwick University but cannot find any.
Would be interested if anyone has found any further research and it included therapeutic dosage.

 

[RichardFromHampshire]

I would likewise be very interested to hear if there is any further research on this subject.

Richard

 

[cugila]

The only research or articles I can find whilst away from my usual place of posting is the Wikepedia entry:
http://en.wikipedia.org/wiki/Thiamine

There is also this article dated Friday 2nd april 2010 but which is actually from January 12th 2009:
High-Dose Thiamine Supplementation Could Reverse Microalbuminuria in Diabetes Patients.

http://www.medinewsdirect.com/?p=625

Not sure if this is any help but it's a start.

Ken

 

[catherinecherub]

Thanks Ken,

I was hoping that there was a recommended dose for diabetics without complications after watching the video.

Not too much to ask is it. :lol:

Time will tell and we may hear more on this subject.

Thanks again,
Catherine.

 

[sugarless sue]

There is an RDA mentioned in the Wikepaedia article. However, any supplement or dosage should be discussed with your GP as there may be interactions with other medications.

 

[phraedus]

Thiamine deficiency

[youtube]UNRaFjdeuZk[/youtube]

Professor Thornalley explained: "There will of course be clinical trials to investigate further the findings we have made using an experimental model of diabetes. However, given the continuing toll of heart disease in diabetic patients, and the emerging benefits of thiamine therapy for diabetics suffering from kidney disease - as reported by our research group last year - I would strongly suggest that those with diabetes are given thiamine supplements."

http://www.innovations-report.com/html/ ... 37768.html

There are four separate pathways that occur in the body that can lead to small blood vessel damage due to hyperglycemia in diabetes.

* Advanced glycation endproducts (AGE)
* Protein kinase C (DAG)
* Hexosamine pathway activation
* Polyol pathway activation

This is a flow diagram of these four pathways

If the body has sufficient thiamine to activate the transketolase pathway the diagram changes to this:

 

[phraedus]

Here are a few inks to Benfotiamine studies.

http://scholar.google.ca/scholar?q=benf ... as_sdtp=on