Please let this be the start of a real cure

[joelcam]

http://www.indexonline.org/diabetes-cur ... vered/1835

Thoughts, comments?

 

[franco]

I have just read this article also . Somehow it doesnt ring true , insulin will always be needed to reduce bloodsugar . I dont quite understand what they are getting at , just building up peoples hopes as usual , like they did a few years ago with orally administered insulin . Although i really hope i am wrong !!!!!!

 

[jimmyt1988]

Interesting find... I guess we'll see.

 

[janabelle]

Franco, you're right unfortuanately
Insulin is required to convert glucose to energy in our body-I'm sure someone will join in and explain it better than that.
I thought the idea sounded a bit simplistic and unrealistic to be a cure, but we live in hope !
Jus

 

[sugarless sue]

This explains quite well why we need Insulin in the body.

Blood Glucose and Insulin

Since diabetes is a disease that affects your body's ability to use glucose, let's start by looking at what glucose is and how your body controls it. Glucose is a simple sugar that provides energy to all of the cells in your body. The cells take in glucose from the blood and break it down for energy (some cells, like brain cells and red blood cells, rely solely on glucose for fuel). The glucose in the blood comes from the food that you eat.

When you eat food, glucose gets absorbed from your intestines and distributed by the bloodstream to all of the cells in your body. Your body tries to keep a constant supply of glucose for your cells by maintaining a constant glucose concentration in your blood -- otherwise, your cells would have more than enough glucose right after a meal and starve in between meals and overnight. So, when you have an oversupply of glucose, your body stores the excess in the liver and muscles by making glycogen, long chains of glucose. When glucose is in short supply, your body mobilizes glucose from stored glycogen and/or stimulates you to eat food. The key is to maintain a constant blood-glucose level.

To maintain a constant blood-glucose level, your body relies on two hormones produced in the pancreas that have opposite actions: insulin and glucagon.

The pancreas has many islets that contain insulin-producing beta cells and glucagon-producing alpha cells.


Insulin is made and secreted by the beta cells of the pancreatic islets, small islands of endocrine cells in the pancreas. Insulin is a protein hormone that contains 51 amino acids. Insulin is required by almost all of the body's cells, but its major targets are liver cells, fat cells and muscle cells. For these cells, insulin does the following:

* Stimulates liver and muscle cells to store glucose in glycogen
* Stimulates fat cells to form fats from fatty acids and glycerol
* Stimulates liver and muscle cells to make proteins from amino acids
* Inhibits the liver and kidney cells from making glucose from intermediate compounds of metabolic pathways (gluconeogenesis)

As such, insulin stores nutrients right after a meal by reducing the concentrations of glucose, fatty acids and amino acids in the bloodstream.

Insulin and glucagon have opposite effects on liver and other tissues for controlling blood-glucose level

( source. health.howstuffworks.com)

Good site for this information, pity about the adverts otherwise I could link to it. Just Google it to get the rest !

 

[HLW]

DKA is caused by lack of insulin rather than high blood sugar isn't it? So even if with good blood sugar levels you'd be at risk of DKA without insulin?

 

[iHs]

http://www.indexonline.org/diabetes-cure-potentially-discovered/1835

Thoughts, comments?

Hi

The wheels will start to turn on this with any luck I'm going to speak to a London liver specialist and get his feedback.

diabetesincontrol.com/articles/diabetes-news/10462

 

[alpha7]

Mice 'cured' of diabetes

hi
This looks interesting but has the usual "cure is years away" caution

informationaboutdiabetes.com/cure-diabetes-58.html

 

[dectjoh]

Type 1 'cure'

http://diabetesnewshound.com/type1/glucagon/

Any thoughts anyone?

Tracy

 

[agavegertie]

No mention was made of Insulin Resistance in the articles in the newspaper or Diabetes sites. Surely this is a main problem for people with Type 2 Diabetes. Your body can be making enough Insulin but if your cells will not accept it you have difficulty.