"The study, which was conducted by ETH Zurich in conjunction with University Children's Hospital Zurich, involved feeding mice two different types of diet (a ketogenic diet and a high fat diet, which causes the liver to become resistant to insulin"
Rather a bold statement to make. This sounds like they already knew what causes IR and then found evidence to support this fact. They may on the other hand just be making an assumption........ They have included this nugget
"It is important to note that the research did not analyze whether the diet employed causes obesity, if given long term."
I think that by high fat diet they mean a normal diet ie regular (or high?) carb such as Eatwell (or the mouse equivalent) with added gratuitous fat and extra mozarella but not a LCHF diet. So they seem to be comparing a LCLF diet against a fatty Eatwell
ETH is however a reputable Technical Institute so there must be a formal paper description of how they conducted this research, but I cannot find it. As in other animal analogues, we need to look carefully at what they used for the diets, and whether the mice were a specially bred strain that is susceptible to diabetes anyway by genetic disposition. This has been the fault behind other such studies I have reviewed in the past.
P.S. I do not know how we would tell the mice.........
I wonder how they established the carb intake level at which a mouse becomes ketogenic, and how they measured the level of ketosis. Difficult doing finger prick tests on a mouse.... So they do say they used special techniques but are their methods valid? No description in the press release - how convenient
In one section they say that if you have IR then you run a high risk of T2D -No ***** Sherlock. But then they say the research proves that keto causes IR, but I see no ships (or proof) in this release.
If anyone can unearth the full report then please post it here, please. Until then I give this a miss.
Postnote: I have now read the formal report, and I still give this press release a miss. The press release is not accurately reporting on the study results - seemingly the opposite conclusion than the scientists make.