I've made an observation that my hypo symptoms begin about 4 hours after eating, which is the time it takes for my stomach to feel actually empty again. This is when I've measured lows with my monitor. But there have been at least a few occasions where I felt symptoms while my stomach still felt full and I wasn't hungry at all, but it's possible that what I feel during those times isn't hypoglycemia (haven't been able to measure those).
Anyways, my question - does your stomach actually have to be "hungry" for you to experience a hypo during reactive hypoglycemia? And if someone's hypos start four hours after eating, does that mean that insulin is highest at that hour? Why wouldn't it be highest at the moment you start to eat, in accompanying the rise of blood sugar?
Maybe a question for my endocrinologist, but I'm interested in others' experiences.
You may not like most of my answer because I've yet to hear from someone who has the same symptoms and when they actually feel the hypo or aware of the hyper then hypo. Firstly because of the stage of development of RH, then diagnosis and of course treatment and control.
Secondly, The spike and how quickly you dump glucose because of the insulin response, then of course the overshoot. Quantifying the when, and how and why, it reacts is individual. The amount of carbs in a meal is important as well, if I have over five percent of certain foods then I trigger the hyper/hypo. It could be more with other carbs.
Your question is an interesting one, but in my experience, it is unlikely that you will hypo on an empty stomach with RH! That is why one of the tests is a 72hour fasting test. Your insulin response is likely to be higher at the point of highest spike, I am assuming that the pancreas would still produce insulin, because that is what my endocrinologist said about me. Because of the secondary insulin response, the overshoot, this is what causes the hyperinsulinaemia in a lot of RH ers! It did for me and increased my weight so much!
What you are describing are the symptoms and you are still learning how to cope with the different symptoms during the process from pre meal to the actual hypo, if, of course you trigger the overshoot by consuming too many carbs.
In my experience, you are describing ' Late Reactive Hypoglycaemia'! This is what my endocrinologist has diagnosed me.
The period between the spike is within the first hour, I hyper around forty minutes, then the overshoot happens during this period and continues until I eat or sleep, but and it is a big but, if I continue to eat carbs, the rebound effect will happen. The experience of having hypers and hypos, gives your brain the excuse to keep telling you to eat more, hence the hunger and craving, I was literally looking for non existent foods to appease my trawling the food cupboards, fridge, freezer, fruit bowl and anywhere including the shop, just to eat something!
Since I have changed my dietary regime to Keto, this hunger, craving has abated and if I behave myself, doing intermittent fasting, the need to continually feed myself has gone away (ish). I still could gladly eat too much but that is habit rather than hunger!
I hope that helps you understand what happens!
Best wishes