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From another thread I was just reading it discusses
https://www.nhs.uk/news/diabetes/are-there-actually-5-types-diabetes/
They also looked at various patient characteristics, complication rates – such as kidney and diabetic eye problems – and use of medications. People were clustered according to 6 main characteristics:
The researchers identified 5 main disease clusters.
So to me 1&2’s look like our type 1’s and LADA’S with and without antibodies.
3’s looks like classic type 2
4’s seem to be the people that respond well to any weight loss of any type eg low cal, low fat, low carb etc and don’t need to restrict carbs as much that I am convinced exist, also currently labelled type 2.
5’s older people, unclear what their IR status, obesity status or insulin producing status is
What happened to what’s currently called type 3 (illness/drug/surgery induced type 1??) and what about TOFI’s who would be a new 3 other than for the high bmi required
Edit. Maybe the current type 3 would fall in the new group 2
edit (the original link has been retired. Here’s a couple of others on the same topic https://www.medicalnewstoday.com/articles/321097 https://www.livescience.com/61917-diabetes-five-types.html). Doesn’t seem like anything came of it as the report is now a few years old but the topic is still interesting
https://www.nhs.uk/news/diabetes/are-there-actually-5-types-diabetes/
They also looked at various patient characteristics, complication rates – such as kidney and diabetic eye problems – and use of medications. People were clustered according to 6 main characteristics:
- age at diagnosis
- body mass index (BMI)
- glycated haemoglobin (HbA1c) – a long-term indication of blood sugar control
- function of the insulin-producing cells of the pancreas
- level of insulin resistance – a measurement of how effectively, if at all, cells respond to insulin
- presence of glutamate decarboxylase antibodies (GADA)
The researchers identified 5 main disease clusters.
- Severe autoimmune diabetes (SAID): this tended to start at a younger age, in people with a relatively low BMI, poor blood sugar control, insulin deficiency and GADA. About 6% of the people in the ANDIS study had SAID.
- Severe insulin-deficient diabetes (SIDD): GADA-negative but otherwise similar to SAID. Identified in 18% of the people in ANDIS.
- Severe insulin-resistant diabetes (SIRD): characterised by insulin resistance and high BMI. Identified in 15% of the people in ANDIS.
- Mild obesity-related diabetes (MOD): characterised by obesity but not insulin resistance. Identified in 22% of the people in ANDIS.
So to me 1&2’s look like our type 1’s and LADA’S with and without antibodies.
3’s looks like classic type 2
4’s seem to be the people that respond well to any weight loss of any type eg low cal, low fat, low carb etc and don’t need to restrict carbs as much that I am convinced exist, also currently labelled type 2.
5’s older people, unclear what their IR status, obesity status or insulin producing status is
What happened to what’s currently called type 3 (illness/drug/surgery induced type 1??) and what about TOFI’s who would be a new 3 other than for the high bmi required
Edit. Maybe the current type 3 would fall in the new group 2
edit (the original link has been retired. Here’s a couple of others on the same topic https://www.medicalnewstoday.com/articles/321097 https://www.livescience.com/61917-diabetes-five-types.html). Doesn’t seem like anything came of it as the report is now a few years old but the topic is still interesting
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