Type 2 Physiological IR/Adaptive Glucose Sparing

[Tophat1900]

You are pointing out that maybe saturated fats can increase insulin resistance. @Caeseji was asking if his current readings could indicate Physiological Insulin Resistance. This is not the same as the diabetic insulin resistance that you are discussing. Physiological IR (PIR) is a situation where the body detects very low glucose and gets worried there won't be enough for the brain, so cells are triggered to reject the glucose there is and it gets sent to the brain. I don't understand the biology behind it but it leads to an increased fasting level and increased levels pre meals. (The base line levels). It does not affect the actual rise we see from before to after eating. It is normally temporary, and can be resolved quickly by increasing carbs by a small amount. It doesn't happen to everyone, or at least if it does, they don't notice because the rises are fairly small, but none the less, consistent.

A small slice of red capsicum does it for me in those situations. It doesn't take much.

 

[Bluetit1802]

A small slice of red capsicum does it for me in those situations. It doesn't take much.

If I recall correctly, when it happened to me, a single shortbread biscuit did it for me!

 

[Guzzler]

Note to self: Buy more Cornettos - for medicinal purposes only. Ahem.

 

[Caeseji]

@Tophat1900 @Tipetoo @Bluetit1802 @Adm_Mad @ickihun Well a lot happened in here whilst I was gone! Thanks all for the insights though, it does sound like it could be that but at the moment my FBG is staying stable at 5.1 for the past few days but again it makes me wonder if the strips have gone a bit wonky. If things get worse I will have to add in a little bit of carbs to try and blunt it at some point but at the mo I am increasing the fat because I may have just been getting too much protein.

I may actually be a little bit dehydrated in the mornings though, that is a good shout. Might have to get myself rehydrated and test instead of just doing it when I open my eyes as that may make a difference. The saturated fats debacle goes deep honestly and I am on the side of Ivor and his contemporaries because like Tophat said we have been seeing a massive decline due to our society vilifying them. Though that's just me in the end and I really do hope your appointment goes well Adm_Mad as it can be so scary to deal with at first.

I'll keep eating to the meter for now and see how carnivory works out for me but please don't tease me with Cornetto's.

P.S. Come to terms with the fact that I am going to be running blindly in the dark with this T2 life but you know what? Helps to have a fantastic bunch of people to do that with right here.

 

[D@n1el]

I have a doubt about Physiological Insulin Resistance or Adaptive Glucose Sparing, and I wonder if anyone could clarify it, please.

Is Physiological IR related only with low carb diet and fasting, or it could happen also with 24-hour/36-hour intermittent fasting alone (with no low carb diet)?

 

[Auto E]

I’ve been reading most of the morning about this, and about how saturated fats (ie fats from red meat, chicken, pork, and processed meats etc) increase insulin resistance so type 2’s trying to eat low carb/higher fat and protein should only eat unsaturated fats like nuts and avocados and fresh fish. No cheese, dairy, processed meat, freah meat with fat in it, etc.

I don’t know about the UK but avocados and fresh fish aren’t exactly cheap in Australia, and apparently eating too many nuts can be bad too.

If carbs = death, too much protein = insulin resistance and kidney problems and fat = insulin resistance and coronary disease which is apparently the biggest cause of death of us type 2’s, exactly what are we supposed to eat?

My answer was going to be green leafy vegetables but apparently they cause kidney disease too.

omg this is how I am feeling these days.

 

[Auto E]

I'm not being argumentative, but that is pretty much the same standard advice T2's are given and it's done nothing to help for at least the last 50 years. Fat is not the enemy, meats are not the enemy, we've been eating these foods for millions of years. If they were as claimed, basically killing us, we wouldn't be sitting here having this conversation. We'd of died off as a species a long time ago. What has had a major impact on chronic disease rates over the last 50 yrs is carbohydrate consumption in the form of sugars, grains and potatoes etc. This creates a state of hyperinsulemia (Too much insulin in your system) and insulin resistance, the pancreas just cannot deal with the amounts of carbs being eaten. This also causes fatty liver. When people go low carb and avoid the grains and eliminate sugar, they improve blood glucose levels, they improve their liver health and remove the massive burden on the pancreas, liver and their general health. Blood glucose becomes more stable. If you want to know more about hypernsulemia etc, check out the links I posted further down.

The low fat advice and only eat 3 weeks a week is absurd. Along with the eat healthy grains advice. I'm not bashing you. So please don't think I am. It is daunting when you are trying to figure out stuff soon after diagnosis. Here are a few links that may interest you.

Ivor Cumin's, https://thefatemperor.com/blog/ - is a bio-engineer with a wealth of knowledge. He covers a lot of diet info, including cholesterol and various other topics. Just scroll through his blog for topics that interest you. He interviews a lot of top specialist in different fields. I've learnt a lot from him And there are plenty of other podcasts available.

For diet and low carb meals etc, take a look at www.dietdoctor.com
@Jim Lahey will recommend Dr.Jason Fung, I think he's a great source of info also.

Good luck with your appointment.

I just listened to a delightful podcast of Ivor's (on Paul Saladino's podcast) and they spent a nice amount of time discussing the (minority of) individuals that do respond poorly to diets high in saturated fats, particularly cheese. So it's a thing, even Ivor acknowledges. The question is - which of us does it apply to? I think we can only know by testing - blood sugar, lipids, etc. I sorely hope I am not one of them because I adore every ounce of cheese, yogurt, and cream in my diet. In fact, I might rather die ignorant if I am one of those unfortunates that is sensitive to sat-fats.

 

[Tophat1900]

I just listened to a delightful podcast of Ivor's (on Paul Saladino's podcast) and they spent a nice amount of time discussing the (minority of) individuals that do respond poorly to diets high in saturated fats, particularly cheese. So it's a thing, even Ivor acknowledges. The question is - which of us does it apply to? I think we can only know by testing - blood sugar, lipids, etc. I sorely hope I am not one of them because I adore every ounce of cheese, yogurt, and cream in my diet. In fact, I might rather die ignorant if I am one of those unfortunates that is sensitive to sat-fats.

That's it, isn't it... who does it apply to?

I love cheese too. And I wonder if cheese being a dairy product has it's own effect separate from that of other different saturated fats. I love Ivor's podcasts.

 

[zerocarbisbest]

omg this is how I am feeling these days.

daily variety of vegetables, variety > quantity. moderate protein, a steak not a whole cow, eggs, good fats, coconut, avocado(homemade guacamole healthier-ingredient variety wise), olives, olive oil, butter from 100% milk, if goats milk better. nuts, variety over quantity.

a decent fasting-feast daily window, during the fast window water, cofee, tea(no milk, no sugar, no sweetners).

if no carbs, vegetabled dont count(althou avoid potatoes) the fasting window will go smoother. also instead of 100g of bread have 100g of egg or fish or anything in the realm of essential fats, essential proteins, vegetables.

when reducing carb intake, careful first days to week, your need for medication ammount may change, be clever about it.

consult a "good" doctor.

(mod edit to comply with rules)