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I have been having chronic loose stools(and frequent movements) from the start of the year. I went to my GP to discuss wether or not it was metforrmin causing this and should I go on slow release. Because I have been on Metforrmin for 4 - 5 years he thought not and reffered me to the local hospital, where I had a colonoscopy which was inconclusive showed some inflamation. The consultant suggested stopping my simvastatin incase that was causing it. After a few weeks my Hba1c check was due so had bloods taken, when I saw the nurse and discussed what had happened she suggested it was more likely to be the metforrmin and said she would discuss with my GP. In the meantime my cholestoral had risen to 6.5 so back on simvastatin. My Hba1c was up to 9.5 so increased gliclazide to 2 in A.M. and 2 P.M. Hand on heart I snack a lot ie 200grm Roasted salted peanuts one night, crisps etc other nights I like my savoury stuff, and little or no exercise. Told nurse this and also recently got a rescue dog so will be getting out and about a lot more this will help. Now on slow release metforrmin and not going to the loo as much and slightly stiffer stools. Having another colonoscopy on 29/11/11, fingers crossed :crazy: