Safety of statins

Alexandra100

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they no longer require fasting results as it has minimal difference they are the current guidelines
@Dax1973 I sometimes fast before the test, sometimes not. I find that fasting leads to slightly raised LDL and slightly lower trigs. I believe that according to much recent medical thinking, trigs and HDL matter, LDL much less. One research study even showed that older women (like me) do better on somewhat higher LDL.
 
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zand

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@zand are you sure you changed nothing else since you started taking fish oil? I used to take fish oil, but nowadays, having read lots of sceptical research articles on it, I prefer to eat 3 portions of wild salmon weekly.
No, I'm not 100% sure, but this was before my low carbing days and the only thing I remember changing way back then was attempting to give up diet coke and other black fizzy drinks. It took me several years to fully kick the diet fizzy drinks habit.
 
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Alexandra100

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No, I'm not 100% sure, but this was before my low carbing days and the only thing I remember changing way back then was attempting to give up diet coke and other black fizzy drinks. It took me several years to fully kick the diet fizzy drinks habit.
Depending on how successful the "try" was, that sounds like quite a powerful strategy.
 

ianf0ster

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.............................................

I can do without the orlistat but my cholesterol is high 3.9 total but 3.2 LDL and only 0.7 HDL and triglycerides are high (too hig to calculate ratio apparently). HDL should ideally be 1.4 or at least 1.2
Strange- because LDL is certainly calculated in the UK and most other countries (unless you pay privately for a more specific lipid profile test). But Triglycerides are measured (in all the cases I know of).

I do agree that your Cholesterol numbers are potentially bad - a Low Carb way of eating would fix that, but for the opposite of why most people would:
Your HDL is way too low and your Triglycerides are apparently way too high. Your LDL is much lower than mine (which is 5.4) and I'm not taking statins (won't consider them until there is some believable evidence that artificially lowering my LDL with CoQ10 depleting statins will be more likely to extend my life than to make it miserable and shorten it. In general people over 60 with higher quartile LDL live longer (all cause mortality) than those with the lowest quartile LDL. (My theory is that those with such low LDL not only get more frequent and more serious infections (LDL required for the immune system), but they have brain fog and/or muscle aches and so decide to give up on life (effectively passively killing themselves).
 

Dax1973

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The original question was should I assume that statins caused swollen neck lymph nodes or orlistat?
Or the combination?

Think statins would be benefcial as my triglycerides were over 7
 

Alexandra100

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Think statins would be benefcial as my triglycerides were over 7
It is often claimed that lowering carbs dramatically lowers trigs. Not in my case (on 20 - 30g carbs daily). Trigs went up, alas.
 

Mbaker

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Not sure that's a valid argument. Our ancestors mostly didn't reach old age (by our standards). They were too busy dying of broken bones, infections (no vaccines or antibiotics) and childbirth (if female). Whether or not you agree with statins modern medicine has drastically increased average lifespans from a couple of hundred years ago. And of course, the T1s on these forums would all be dead anyway. :)

Life expectancy - Wikipedia
Not necessarily very accurate, but interesting anyway.
hmm. You gave the reasons which support my view. My research shows that when you did not die of say disease or death during birth, life span was full. I actually meant parents to grand parents, when I was a child 1 in 3 for example got cancer, now 1 in 2, this is off point, but demonstrates that drugs tend not to fix thing.

When I was a child statins were not invented and people had less strokes and heart attacks, the trajectory is upwards despite statins being the no.1 drug - this is called a failure of proof in my book, 1987 was a terrible year for humanity. Then there's the hard end points proved with differing datasets such as the large Nhanes - this categorically shows it is overall better to have higher cholesterol; another study shows older women are better off with higher cholesterol. It may be a consensus that LDL is a problem, but this is not science. Science needs to be repeatable and make sense. LDL is in every cell in our bodies and 85% is made in the body, why would our own bodies try to kill us.

Your points are not related to statins. Statins are only of use (on their contested numbers) if you have had an event, not before. If you have had an event you will live on average an extra 4 or so days, a terrible return for a drug that can muscle ache and increase the risk of diabetes (2 sources Asseem Malhorta, Malcolm Kendrick). If statins are so great why are the results of trials locked up in Oxford, why do some trials get rid of those adversely affected (and not count them) with a run / wash out in phase - that's called cheating.

On your wider point, drugs have increased lifespan, but not health span,. Some drugs are essential such as Insulin, others mask a sympton that can often be changed with lifestyle choices . I believe the average 55 year old on around 5 pills. Personally I would rather live healthy to 80 and drop dead than 85 with the last 10 years fragile, in and out of hospital and the like.
 

Mbaker

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why would our own body try to kill us?

Cancer cells are in allof us and just need to be activated!
There has to be a trigger. Some with agendas have said for example red meat (rubbish based again on historical context and the embarrassing relative risk levels). I believe it is mainly down to processed food, environmentals (pollution such as car fumes, sprays, food additives, heavy metals, chemicals such as those sprayed on veg, lack of essentials such as vitamin D, change from manual work to sedentary, etc).

Compare how we live now to say a traditional Red Indian. In the thrust of the thread regarding safety of statins, the research I have done shows that for example that a clean Keto diet works well with chemotherapy, reducing symptoms, some have gone further, but authorities tend to only legally allow Keto when cancer has gone to the later stages, and not a side by side from the start. This makes sense when many cancers are glucose based (video with Professor Thomas Seyfried below)

Rather than meat causing cancer, Paleomedicina use a meat exclusive diet for cancer treatment (of course this is a specialist intervention that should not be tried by an individual at all).

 

EllieM

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The original question was should I assume that statins caused swollen neck lymph nodes or orlistat?
Or the combination?

In my experience of an allergy to an antibiotic which was a mix of two others, my GP guessed as to which one was more likely to cause the problem and gave me the other. He then had to change over again as it turned out I was allergic to the one that was supposedly less likely to cause issues. So, in my (limited) experience at least, you just have to use a process of elimination to identify the culprit. No easy answers. Allergies vary from person to person.

What does your doctor suggest that you do?
 
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Dax1973

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Good idea was going to try statins without orlistat.

The Dr. didn't have a clue and just did multiple blood tests and still didn't have a clue!

I know more than practically any dr about all the medical conditions I have - especially the two worst ones and it was the best idea I came up with. Problem is had a covid jab 3 of the 5 x it happened took both pills 3 times it happened if not 4 and also had psoriasis which can cause it where I stopped treatment for 30 days (as you have to every 4 months when it ceases working).

Had allergic reactions to all 3 covid jabs - once calling ambulance, once going to hospital and to the pfizer was too ill to call the ambulance and thought I wouldn't survive and there won't be a 4th!

Both pills can cause swollen lymph nodes, could be either or the combination of the two and possibly the covid jab thrown in too.
 

KevKS

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Wow! Whoever told you THAT was high? Mine was 7.3 for years and, with diet, dropped to 6. Then I took a statin substitute from a health food shop and got it to 5.3 but it's never been lower than that!
What was the substitute?