Trajenta study - helps mices with stroke...?

C

Cowboyjim

Well-Known Member
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1,294
http://www.pharmafile.com/news/176316/trajenta-may-reduce-stroke-damage
Double plus good eh?
Another example of DM meds having beneficial "side-effects"...
Those poor mices need all the help we can give them... yes, I've read HHGTTG! 8)

"Boehringer Ingelheim’s diabetes drug Trajenta could one day be used to minimise the effects of brain damage following stroke.Scientists in Sweden made the finding in a study of diabetic mice. The Boehringer-sponsored trial at the Karolinska Institutet saw that Trajenta (linagliptin) stimulates neuroprotection as well as lowering glucose."

see also this re met
http://www.drugwatch.com/2012/12/04/study-diabetes-drug-metformin-may-helps-to-fight-ovarian-cancer/
 
Sid Bonkers

Sid Bonkers

Well-Known Member
Messages
3,976
Type of diabetes
Type 2
Treatment type
Diet only
Dislikes
Customer helplines that use recorded menus that promise to put me through to the right person but never do - and being ill. Oh, and did I mention customer helplines :)
It seems quite common for a drug designed for one thing to be found to be beneficial in another area like some of the pain releif drugs I have tried in the past were designed for epileptics, depression etc

I believe that Viagra was originally a medicine designed to manage blood pressure!! You couldnt make some of this up could you?
 
H

hanadr

Expert
Messages
8,157
Dislikes
soaps on telly and people talking about the characters as if they were real.
It's the way oif the world
the chemists synthesise molecules and the pharmacologists try to find a use for them. I believe it happens in othe fields too;weren't selotape and post-it notes discovered by accident ?
Hana
 
C

Cowboyjim

Well-Known Member
Messages
1,294
I agree but there is an extra incentive of late because of the state of the pharm industry which faces amongst other things the so-called "patent cliff" whereby some cash cow drugs will shortly no longer be their exclusive preserve.
Not quite sure how this will affect us but there is the possibility of cheaper drugs coming when other companies get their hands on some of these cash cows.
http://www.ibtimes.com/big-pharma-facing-patent-cliff-declining-rd-returns-919311
Drugs cost so much to develop it is not surprising they constantly look for new ways to widen the market.
It is a perhaps a good thing but on the other hand it sort of in my mind is not quite as impressive as regards their plan of attack on illness. It seems a little less systematic and more serendipitous. But as you say this has led to all sorts of innovations such as nylon and post-it notes... maybe even bubble wrap I dunno...
But I wonder if there is some department in each pharm company responsible for trying out all their drugs on everything just in case... 8)
Science is incredibly interesting but the haphazard way it has sometimes developed does leave this man slightly worried.
Not so long ago, for example, not a few majors officially gave up on ever making blue LEDs. It was left to a very insightful Japanese man in a fairly obscure lab to show them what they were missing. He not only created the world's first useful blue LEDs but also white LEDs and violet lasers... an astonishing achievement!
http://en.wikipedia.org/wiki/Shuji_Nakamura
 
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