I got this from a hospital working with Stem Cells. Anyone with lots of money to spare can always do this, but for me, I don't have the cash laying around.
Clinical research has clearly demonstrated that Mesenchymal Stem Cells (MSCs) implantation brings better control of blood sugar to a majority of diabetes mellitus patients by reducing their dependence upon insulin and/or other anti-diabetes medication.
1. The implanted stem cells multiply and differentiate in the body to repair the injured islet β cells in the pancreas;
2. Stem cells can improve or recover the function of islet β cells;
3. Stem cells can produce cytokines, which can promote regeneration of islet β cells;
4. Stem cell therapy can decrease insulin resistance;
5. Stem cells have immune-regulation function, which may also play a part in recover from diabetes.
The Diabetes Center of Puhua International Hospital focuses on innovative and effective treatments for patients with type 1 and type 2 diabetes. The Center uses a combined approach: stem cell treatment with conventional therapy. This combined method has been proven to be safe and effective: to date, 70% of our patients have gained clinically significant improvements after stem cell treatment, including:
1. More stable blood sugar levels
2. A reduction in medication, including: reduced/discontinued insulin, reduced/discontinued anti-diabetic medications.
3. Reduction in diabetic complications, including: improved eyesight, less diabetic neuropathy pain, better systemic blood circulation, diminished protein in urine/improved kidney function.
Here are personal testimonials from just a few of our patients:
http://www.puhuachina.com/en/stem-cell- ... sulin.html
http://www.puhuachina.com/en/stem-cell- ... manwu.html
http://www.puhuachina.com/en/stem-cell- ... salem.html
http://www.puhuachina.com/en/stemcell-t ... tareq.html
You will find additional patient case-reports at:
http://www.puhuachina.com/en/case-studies.html
While it is important to know that patients differ from one other in many ways, it is also important to acknowledge that most (at least 70%) of the diabetic patients treated with SCT at PIH have experienced clinical benefits.
Therefore, it is well to acknowledge that the results of SCT for diabetes will vary from patient to patient, and that the improvements are normally gradual and progressive.
Indications for stem cell therapy (SCT) for diabetes:
1. A diagnosis of type 1 or type 2 diabetes;
2. 3-75 years of age;
3. The blood sugar that is poorly controlled with appropriate medical/insulin therapy;
4. Otherwise functional general health, with mild/moderate diabetic complication(s);
5. Good compliance;
6. Obstinate diabetic ulcers that have failed conventional treatment.
About the stem cell treatment (SCT):
MNCs and MSCs implantation are used in the treatment for diabetes, combined with conventional therapies:
About stem cells:
MNCs: "MNCs" is an abbreviation for mononuclear cells, better known as "monocytes." These cells are isolated from the patient's own peripheral circulation. The term "MNCs" actually refers to a selected population comprised of several kinds of stem cells.
(You may learn more about our MNCs program at:
http://www.puhuachina.com/en/mononuclea ... ogram.html )
MSCs: MSCs (Mesenchymal Stem Cells) are collected from the umbilical cord blood. Because MSCs are primitive cells, they have very low immunogenicity. Therefore, it is unnecessary to have matching tests before transplantation and patient doesn't need to take any immunosuppressive medicine after the treatment. That's one of the advantages of MSCs.
About the stem cells delivery:
There are two ways to deliver stem cells into the body:
a) Interventional therapy: in this method, stem cells are infused directly into the pancreas through a femoral artery catheter. Once infused into the pancreas, the stem cells can proceed to repair the injured islet β cells and promote the recovery of the pancreatic function.
b) IV injections: the stem cells circulate around the whole body to repair the injured blood vessels and improve whole body, including the pancreas, via the systemic circulation.
Combined therapies:
1. Insulin/oral medication: the PIH medical team will adjust the insulin or oral medicine dose in accordance to patients' actual blood sugar levels both during and after the treatment. Patients should expect to reduce their insulin or oral medicine gradually;
2. Traditional Chinese Medicine (acupuncture, massage and/or Chinese herbal medicines);
3. Diabetic diet and counseling;
4. Exercise counseling.
Possible Side effects:
Possible side effects include: headache, fever, weakness, and dizziness. Side effects may happen in the first 24 hours or out to 3 days after the injection. These side effects are usually temporary and quite mild. The usual mild side-effects pose no threat to the patient's health and will be expected to adversely affect the therapeutic outcome.
Measures of Therapeutic Success:
1. Becoming free of the need for insulin and/or other diabetic medication;
2. Becoming less dependent upon insulin and/or other diabetic medication;
3. Less risk of hypoglycemia;
4. Recovery of islet β cell function (more natural insulin/less need for injection or medication;
5. FPG, 2HPG and HbA1C trend toward normal;
6. Diminished frequency of of diabetic symptoms,
7. Clinically cure/improvement of diabetic complications (neuralgia, ulcer, nephropathy, etc.)
Regarding Follow up:
After your discharge, PIH will keep in touch with you (emails or by phone, per patient). Patients are asked to report blood sugar and medication records to PIH at convenient intervals. The PIH physicians will offer advice in accordance with indication and patient request.
If a patient has any questions, they can always communicate with their PIH team, and many patients do so long after discharge.
Treatment time & estimated cost:
Generally, the treatment plan can be finished within 2 weeks.
The estimate cost for the 2 weeks' treatment is about 17,000USD~23,000USD
Please be aware that PIH makes different (individual) treatment plans for each patient, and the final cost depends on the individual treatment plan, and other variables.
The cost uncertainties mainly depend upon the dosage and type of stem cells, as well as the approach (IV/Interventional.) These details will are discussed in detail with patient as the individualized treatment plan evolves.
Estimate Average Cost is Inclusive of:
Stem cell implantations;
Daily IV medicines;
Chinese massage;
General medical services; Doctor's visits and examinations, laboratory tests, etc.;
One room for the patient and 1-2 people who accompany the patient.
Estimate Average Cost is Not Inclusive of:
Emergency management or treatment for unrelated illness
Discharge medications
Unexpected expenses such as prolonged hospitalization.
Food