This is what was posted on another site many years ago. I personally do not eat pizza but the method is very good for very high fat meals of any type.
>
> Here is the technique doctors often teach in Italy to deal with pizza,
> which
> I agree is not an easy task (even for Italian diabetics) especially when
> you
> eat pizza at night and, as you said, you can't really walk it off (and in
> Italy we love eating pizza at night!).
>
> The idea is that when you eat the pizza, you bolus (normal bolus) for the
> amount of carbohydrates you estimate for the amount of pizza you eat. For
> a
> whole pizza from Tuscany/Liguria (the zones where you are going), which is
> pretty light and thin, I would say about 90-100g carbs (a Southern Italy's
> pizza is often a bit heavier). Let's say you eat it at 8pm. This insulin
> should keep your blood sugar ok until 10-11pm. At that time you do an
> additional bolus for about 1/3 of the insulin you did before but as a
> Square-Wave
> Bolus over 4 hours. (If you do not do this additional bolus, values will
> go
> up during the night)
> In my case, it means 6 U of insulin when I eat the pizza and 2 more at
> 11pm
> (released from 11pm to 3am).
>
> I am not sure what's the theory behind this method and I was rather
> suprised
> the first time I heard it but... it does work quite well for me.
>
> However, Diana's suggestion of eating some salad or vegetables, I would
> add
> before or together with the pizza, will also definitely help.
>
> Of course, be careful if you try what I wrote you (i.e. test during the
> night) and... let me know!!
>