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  1. W

    How Metformin works, AKA "Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides"

    My partner is an academic developmental biologist, and came across this paper on the mechanism of metformin. https://www.science.org/doi/10.1126/science.ade3332 She says: She adds: However, she found this Twitter thread which puts it into context and gives a summary of current thinking -...
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    Second-hand or shared continuous glucose monitors?

    As a Type-2, managing my condition through diet alone, and having read Jenny Ruhl's "Diabetes 101", I'm concerned that post-meal blood spikes are the thing to watch. I check these with a cheap SD Code-free glucometer. This is adequate. Nevertheless, I can't see what happens between meals, or...
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    Where can you get a Calcium Score (AKA Agaston) test in the UK?

    A follow on from my previous question about Kraft tests (link omitted, I seem unable to post links). I am a type-2 and I am concerned about possible future cardiovascular disease. My GP suggested I take statins, although my cholesterol levels have since improved. I've heard about the calcium...
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    Where can you get a Kraft Test in the UK?

    I've heard about the Kraft Test, that it is a variant on the glucose tolerance test but which also measures insulin levels as well as glucose levels. I gather it might have detected my T2D trajectory much earlier than it was. I am wondering why it is not used and would like to find out the...