I was prescribed Xenical about a two years ago. I had to lose a stone on my own before they prescribed it and my weight loss actually slowed down once I started taking it
I don't tend to have too much trouble losing weight by eating less and moving more, but I do struggle to keep it off... I normally lose two stone and put a stone back on. I am getting thinner, but very, very slowly.
Wish I could be more like Sid Bonkers and keep the weight off long term.