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Gliclazide

rogpt51

Member
Messages
9
Hi put a sep positng on over last week or so re recent T2 diagnosis but having started a 2 x 80mg dose of Glic on Weds this week (to hopefully work with my MF 2 x 2 tabs per day) already seeing my post meal BS coming down a bit to in the 7's range from readings still averaging 10.5 to 11.5 when I get up in the morning. On MF alone this wasnt really happening but with the Glic I am already feeling a bit better throughout the day and spikes experienced during first 8 weeks post diagnosis feeling lower - does anyone have recent experience of moving onto combination medication, trying to understand if all the benefit from taking Glic is fairly immediate or whether its more gradual - I sense from my GP that I still have work to do re my morning readings if I am going to have any chance of avoiding insulin injections coming onto the agenda very soon - he has given me until end of first week in September to demonstrate single figure readings! Weight is not really an issue for me at the moment either - Thanks guys Roger
 
The other aspect I meant ask was in connection with sporting activity eg golf, cycling and racket sports - with Glic do I need to be ultra careful if for example my BS is running in the 7's before embarking on activity?
 
Hi

If you look at the NICE guidelines on the web, you'll find that there is a 3rd level of treatment open to you beyond MF and Glic which makes you at the '2nd level' currently. There are various options other than insulin e.g. the glitazones or sitaglitpin which I'm now on. Also alternative injections to insulin (see the Medication section). Interestignly when I suggested I needed to go onto insulin at my last GP appointment my GP said it was a last resort hence I was offered a glitazone or sitagliptin; the latter has certainly reduced my spikes. GPs have a widely varying view of insulin use for type 2s. My understanding and experience with Glic is that it should start working within a few days. If Glic works for you then the advice is to be aware of possible hypos especially after lots of exercise. Glic didn't help me that much hence I've never been near a hypo. Personally I would take more note of the BS level 2 hours after a main meal and not morning readings due to the liver-dump effect. Most GPs tend to go by the HBA1c result which gives a good average measure to determine what level of medication to prescribe
 
When I had Glic added to my Metformin I saw the benefits within the first week. The downside is the risk of hypos, and this is a very real risk for you especially if you do exercise (I don't!). I now never go anywhere without glucotabs and a muesli bar, and always test before driving, and stop every two hours to retest. Fortunately I'm quite hypo aware... but when I start "going off" it still takes me slightly by surprise, hence the necessary discipline of carrying glucose and testing.
 
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