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I have concluded that people with my genetics turn on and off insulin resistance./the 'thrifty gene'

Discussion in 'Diabetes Discussions' started by yetta2mymom, Jul 29, 2016.

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  1. yetta2mymom

    yetta2mymom Don't have diabetes · Well-Known Member

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    Hi

    On a severe Atkins diet with my genetics (glucose tolerance test rises for over 2 hours and then heads south, do not necessarily lose weight on a severe Atkins diet, many people in the near east do this), that my body is turning on insulin resistance until my blood sugar rises (what ever that means) and signaling the pancrase to do its thing. If you want I can give all sorts of reasons why this is likely so. The question arrises how does my body do this. Is there some chemical needed for sugar to become fat other than insulin which could be substituted or done without. Do you have any knowledge of what happens when a person becomes a severe type 2 diabetic? Could my body turn that on and off. Yes I am simulating a severe type 2 diabetic on a strict Atkins diet.
     
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  2. zand

    zand Type 2 · Expert

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    Honestly I would stop worrying about it. You have found a diet that suits you and keeps you well. If I were you I would concentrate on helping your wife with her actual T2 rather than worrying about your 'simulated T2'.
     
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  3. azure

    azure Type 1 · Expert

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    What you're describing just sounds like normal insulin resistance to me.

    As Zand says, if your diet is working for you then that's the most important thing. If i remember correctly, your HbA1C was normal. The normal range is just that - a range. I sometimes test my non-diabetic friend's blood sugar out of interest, and I get varying results depending on what they've eaten. But that doesn't mean they have problems.

    If you've found a way of eating that suits your body then stick to it :)
     
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  4. Lamont D

    Lamont D Reactive hypoglycemia · Master

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    You have an overactive pancreas, which creates excessive insulin! That's why you 'go south'!
    You eat a diet that suits that condition, which stops the excess insulin!

    That's about as much as you can do!
    The whys and wherefores are for specialist endocrinologists.
    Especially the rare types.

    I would concentrate on getting the wife on a low carb diet to improve her health!
    If you need answers to those problems, you will get some great information from the forums knowledgeable posters.
     
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  5. yetta2mymom

    yetta2mymom Don't have diabetes · Well-Known Member

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    Hi

    Obviously you are not a scientist nor do you have the high drive I have to help humans. If I can figure this out who knows where it may lead. If the body can turn off insulin resistance maybe we can learn something about doing it. If you care one of the ways that makes me pretty sure this is what happens is anecdotal evidence. I have talked to people from the Near East (I am nosy as you can see). I started to do this as one adjugated man said 1/2 the people in India were prediabetic but they didn't become diabetic (me). He also said that during pregnancy his wife's blood sugar took off with one grain and had no problem with another grain. I have asked every person who looks like they are from the Near east and everyone admits to this problem. I assume this is a case where the medical profession is asleep at the switch. A relative has my gene and had the same sugar experience. After pregnancy the (stupid?) doctors looked at her "hunter" gene glucose tolerance test and said she was sure to become diabetic within 2 years (over 40 years ago). I have offered to help fund a study of women taking a glucose tolerance test before during and after pregnancy. One nibble but money doesn't talk. I cannot even give a substantial amount away.
     
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  6. yetta2mymom

    yetta2mymom Don't have diabetes · Well-Known Member

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    Hi
    I have this drive to help humans. If we can figure this out would it say something for type 2 diabetes? Why should I be as self centered as you imply. You are not in a minority. Is there something wrong with not being self centered?
     
  7. yetta2mymom

    yetta2mymom Don't have diabetes · Well-Known Member

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    Hi
    If the body (for a large minority) of people can turn off insulin resistance maybe we can copy how it does that. Without my autoimmune reaction in 1957 many people in the Near East have no problems (that I know of) except for not being able to control sugar in pregnancy and when they change from a food deprived society to a richer one they tend to become fat and often aquire diabetes.
     
  8. yetta2mymom

    yetta2mymom Don't have diabetes · Well-Known Member

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    Hi

    You are asking a scientist to stop from being curious. You are asking someone to be very self centered. You are asking someone to be immoral.

    Neil
     
  9. Indy51

    Indy51 Type 2 · Expert

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    For someone who claims to be interested in other people, you seem remarkably self-obsessed. How many threads have you started about yourself and your particular condition now? I can't recall you contributing to any topic on the forum beyond your own. You ignore every suggestion for other solutions other than your "hunter gene" fixation. I truly think everything that could have been said on the topic has already been covered, so I wonder why on earth you keep on and on and on about it? I doubt if anything new is going to come out of yet another discussion. [​IMG]
    [​IMG]
     
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  10. zand

    zand Type 2 · Expert

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    Far from it, I believe you should be helping your wife. You say she tried your diet and then had a hypo. Did the scientist in you not realise that maybe this meant she could reduce the drugs she was on? Did you suggest she see her GP with this aim? Did you not realise you could help her to get her T2 into remission? Have you researched the drugs she is on? Some of them may wear out the pancreas more quickly, leading to complications further down the line. That's where you need to start, at home.

    What you yourself have may be RH. You need to see an endocrinologist about this. The science has already been discovered, you are trying to reinvent the wheel.
     
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    #10 zand, Jul 30, 2016 at 6:56 AM
    Last edited by a moderator: Jul 30, 2016
  11. zand

    zand Type 2 · Expert

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    How dare you judge me? Why do you think I post on this forum if not to help others?
     
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  12. Jaylee

    Jaylee Type 1 · Expert
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    Hi @yetta2mymom

    With the utmost compassion & respect. (I've read your other thread too.) http://www.diabetes.co.uk/forum/thr...-a-diabetic-uses-a-severe-atkins-diet.105008/

    I feel you maybe focusing your hypothesis by "simulating" diabetes in the wrong area..?!!

    Have you thought about an appointment with a memory clinic to rule out any form of early onset with dementia or Altziemers?

    I have had experience of a similar mindset with my father. Though this was regarding his consistent misunderstanding & perceived fault with a motor vehicle. (Which could not be found.)
    This reasoning initially was overlooked & put down to his age & chractor. But the day came when he had totally forgot how to drive...

    Wishing you all the best!

    J>
     
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  13. azure

    azure Type 1 · Expert

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    @yetta2mymom Lots of what you've mentioned in your previous thread has been figured out already. You asked whether an Atkins style diet could be 'the answer' to Type 2? Well, yes, and that's been explored for more than 10 years. Indeed, this forum itself promotes carb reduction as an aid to diabetic control. So it's already been spotted and already being studied and being done.

    The propensity of people from S Asia to develop diabetes is probably to do with their genes.
     
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  14. azure

    azure Type 1 · Expert

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    I don't understand what you're trying to say. There is no switch to flick insulin resistance on and off. It doesn't work like that.

    It's been suggested that you may have Reactive Hypoglycaemia - an Endo could help with that. I personally feel you may simply have a reduced Phase 1 insulin response, but I'm not a doctor. Again, if you feel unwell or concerned, you should see a doctor.
     
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  15. catapillar

    catapillar Type 1 · Well-Known Member

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    & that's how gestational diabetes works - ladies can become insulin resistant when they are flooded with pregnancy hormones, when the pregnancy is over, the insulin resistance fades because no more pregnancy hormones are interfering with insulin sensitivity, but the fact they have had that reaction flags a higher risk to developing type 2 - a risk is just that, a risk not a certainty, some ladies who have had GD might go on to have type 2 in the future, some won't.

    While you seem perfectly happy to query the whether the doctor who told your relative with GD that she had an increased risk of type 2 is s stupid (and perhaps he might have been to phrase the warning in the way you describe) I'm afraid I'm having to try ever so hard not to raise the same query about your understanding of diabetes.

    Again, you aren't "simulating" any kind of diabetes by following a low carb diet. What you are doing is, simply, following a low carb diet. If your body is reacting in an unexpected or unusual way to food, that could be because of some underlying insulin resistance or reactive hypoglycaemia (both of which you may indeed be treating with a low carb diet, just as many people treat these conditions with low carb diets) - why not discuss these possibilities with a doctor.
     
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  16. Indy51

    Indy51 Type 2 · Expert

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    Out of interest (or rather, bemusement), I've collected the topic titles that the OP has opened on this forum since joining March 2016 - 13 in all and all variations on the same theme:

    I have concluded that people with my genetics turn on and off insulin resistance
    What is the expected blood sugar reading if a diabetic uses a severe Atkins diet?
    Can you control diabetes purely by diet?
    Severe Atkins style diet has about 8 year effect on sugar
    Atkins diet no different than any other
    Why I guess Gestational Diabetes Exsists
    I have eaten very low carbohydrate diet for (guess) 40 years
    My body fights to not lose weight (annoying)
    Physical problem use Atkins diet. Any suggestions?
    Anyelse with my problem? Forced into your diet
    Prediabetes are genetic variants
    Is (GTT diagnosed) Prediabetes actually a genetic trait?
    Prediabetes are genetic variants

    I'm still confused about what the OP actually expects to gain from this support forum?
     
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  17. Jaylee

    Jaylee Type 1 · Expert
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    Wow Indy,

    That collation of titles reads like the lyrics to a Manic street preachers song. With the last thread title as the chorus...?
     
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  18. ickihun

    ickihun Type 2 · Master

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    I'm wondering why insulin resistance fights weight loss too.
    Someone on here once said insulin doesnt add weight. For some, I corrected as I assume insulin is preventing weight loss.
    So if not insulin nor excessive food then what?
    This OP wonders like me what causes insulin resistance to not be deminished or lost when many sufferers loss weight even.
    I'm eating small amounts of food. No way enough to sustain my nearly 20stones. I still do not lose weight. I exercise, I still dont lose weight. I go low carb still no loss other than a rebounding few pounds. Loss then gain.
    Why is my body in survival mode when im not starving nor walking 100s of miles a day?
    OP is looking for answers from posters who look like they have the diabetes game beat.
    As already pointed out..we are not medically trainer nor specialists in the field. OP would be better off quizzing his/her endocrinologist.
    They know far more than I. Sorry. I cannot help with your enquiry either.
    If we knew the answer we would be rich too.
    I wish the OP the best of luck in finding a solution to supplement healthy food and exercise for insulin resistant sufferers.
    Ps. Not all posters are not insulin resistant or at least not as severe as some. Fat will always be the whipping boy!
    Ive had it all my life. Tell me something I dont know, being fat isnt healthy!
    I feel your frustration too.
    Your a proactive person but this gets us all fed up.
    There is no solution other than an assisting diet, my friend. Kind regards in your plight. :)
     
  19. ickihun

    ickihun Type 2 · Master

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    That is not a bad point to make.
    Maybe my body has forgot to lose weight on a variant of dementia/Alzheimers?
     
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  20. azure

    azure Type 1 · Expert

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    @ickihun There is a lot of info on the site about insuljn resistance if you do a search.

    No, it's the insulin resistance making it harder for you to lose weight so its a metabolic thing. There are various threads about insulin resistance here if you do a search :)
     
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