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Impact of Rituximab on Blood Glucose

Discussion in 'Type 1 Diabetes' started by mattw, Jul 11, 2020.

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  1. mattw

    mattw · Member

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    Does anyone have experience of this?

    I am on a quick (4 doses at one week intervals) course of R for a just diagnosed chronic leukemia ("Hairy Cell"), which is fortunately well understood with a successful and routine treatment regime which puts it into long term remission nearly all the time.

    I find that my control has slipped, and I wonder whether the treatment is having an effect?

    My initial indication is that I may have to double my insulin to carb ratio.

    I'll be doing a test in the morning, but comment from anyone with experience of the treatment would be helpful.

    (Me: 20 years Type i diabetes, earl 50s, last A1c was 7.3%, Average BG has jumped from around 9 to 10+ mmol/l. I am on MDI and a Freestyle Libre)

    Cheers

    Matt
     
  2. urbanracer

    urbanracer Type 1 · Moderator
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    Check your PIL?

    Some websites list high blood sugar as side affect, some don't.

    https://www.webmd.com/drugs/2/drug-5206/rituxan-intravenous/details/list-sideeffects
     
  3. Peter03

    Peter03 Type 1 · Well-Known Member

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    I was on rituximab for 30 months, it never affected my in insulin needs, however all the steroids played havoc with my blood sugers, I have been in remission for 5 years now, so good luck and keep well
     
  4. mattw

    mattw · Member

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    I've increased my insulin ratio by 50% (ie 1u / 5g to 1u / 3.5g), and it is now hitting the ball park.

    So we'll continue to play...
     
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