I've been on maximum dose Metformin and Gliclazide for 6 years or so and at my GP appointment last week my HBA1C was 7.7 up from 6.7 last time and my own BS readings showed my BS going anything up to 15 two hours after a meal. I expected and even suggested that I go on to insulin as I was having to be extremely careful with food quantities and carbs to maintain even 7.7 HBA1C. My GP said I should I should not be trying to eat 'abnormally' (or be using a meter!) and after a some 'discussion' we agreed I would go onto Sitagliptin (Januvia). My GP warned me to be careful of hypos. I wasn't too worried as Gliclazide had not really worked for me and what I read about Sitagliptin is that it is self-controlling and doesn't itself add to hypo risk as it stops working as BS reaches normal levels. Anyway my BS measurements over the last week show a dramatic drop in my BS levels e.g. 6 to 7 two hours after a meal and also 6 after a gym workout after a small breakfast showing hypos not being an issue. For me Januvia is amazing (so far) with no apparent side effects. Perhaps it won't last and as my Type 1.5'ish diabetes, my diagnosis, doesn't exhibit the typical Type 2 insulin resistant symptoms it may not work for others. Anyone else any experience of Januvia?