I know that stress can have a negative effect on blood sugar levels, but what about pain?. I've had quite severe pain from my neck all weekend after some osteopathy treatment. Not particularly stressed about it, in fact I used it as an excuse just to sit quietly and read a good book. However my blood sugar levels have been a bit higher than I would expect. My fasting level this morning was 6.1, when I would usually see a high 4 or low 5. Is there something about the way the body responds to pain that increases blood sugar.