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Statins - good or bad - what does the research say?

Discussion in 'Diabetes Discussions' started by Indy51, Jan 1, 2016.

  1. Indy51

    Indy51 Type 2 · Expert

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  2. Osidge

    Osidge Type 2 · Well-Known Member
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    Interesting that the study only *associated* statins with CKD and did not indicate a causative relationship.

    Doug
     
  3. dannyw

    dannyw Type 1 · BANNED

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    In a similar way cigarettes are "associated" with cancer. Never actually been proven beyond doubt although evidence is gaining.
    Tough choice.
     
  4. Southbeds

    Southbeds Type 2 · Well-Known Member

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    Now I have stopped taking statins just hope my legs will stop hurting when I walk
     
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  5. Bluetit1802

    Bluetit1802 Type 2 (in remission!) · Legend

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    It's also interesting that NICE recommends that people started on statins should have a 3 month kidney function test followed by annual ones, and great care should be taken before prescribing statins that the person has properly functioning kidneys.
     
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  6. PatsyB

    PatsyB Type 2 · Well-Known Member

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    I am still on statins and still do not know whether they good for me or whether to stop tkaing them as I have no side effects from them at all?
     
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  7. Osidge

    Osidge Type 2 · Well-Known Member
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    The amount of research and the availability of genetic (DNA) research results is changing that.

    Doug
     
  8. Osidge

    Osidge Type 2 · Well-Known Member
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    A number of medications have prescribing rules around kidney function.

    Doug
     
  9. Bluetit1802

    Bluetit1802 Type 2 (in remission!) · Legend

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    Most likely for very good reasons. :)
     
  10. Bluetit1802

    Bluetit1802 Type 2 (in remission!) · Legend

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    Patsy, only you can make that decision after reading all the pros and cons.
     
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  11. dannyw

    dannyw Type 1 · BANNED

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    Agreed, very similar to statins really. Compared to 5 years ago, the growing voices of concern amongst both patients and the medical profession has increased dramatically.
     
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  12. Osidge

    Osidge Type 2 · Well-Known Member
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    @dannyw I am not sure that the research on tobacco is directly comparable with that on statins.

    Doug
     
  13. Oldvatr

    Oldvatr Type 2 · Expert

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    I have tried most of the branded statins at some time over the last 10 years, all had the same result:- No reduction in lipid panel, but debilitaing arm and shoulder pain after the first week or so. I have had a background Ezetemibe dose for some time, but again it does not seem to help lower the LDL. Have now given up on all of them, and doing LCHF diet instead, will know next week if it has had any effect.
     
    #13 Oldvatr, Jan 1, 2016 at 2:54 PM
    Last edited by a moderator: Jan 1, 2016
  14. Southbeds

    Southbeds Type 2 · Well-Known Member

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    Just hope it is not to late
     
  15. dannyw

    dannyw Type 1 · BANNED

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    Well, neither of us would know as much of the on going research is as yet unpublished and in some cases contradictory. However, the trend in public opinion ( not scientific research ), and amongst the medical profession is that of growing suspicion and concern. 60 or so years ago, smoking wasn't deemed a health risk either.
    Still, even this small ( unscientific ) poll here suggests quite a large number of members have concern over statins.
     
  16. DavidGrahamJones

    DavidGrahamJones Type 2 · Well-Known Member

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    If you have used statins, did you experience significant side effects from using them?

    I was one of those who experienced a lot of leg muscle pain, very poor sleep patterns and brain fog. So, not an opinion, not a concern, hard fact, anecdotal maybe, but a fact. I stopped taking statins three years ago and although the leg muscle pain has reduced dramatically, there is still some.


    I have no way of telling what the long term side effects are, especially as statins prevent the uptake of CoQ10, a fact that even Merck Pharmaceutical recognised in their 1990 patent application to include CoQ10 with the statin. Unfortunately there was no scientific evidence to show that ingested CoQ10 would make up for the CoQ10 missing although in some countries it was prescribed along with the statin.

    The fact that statins affect different people in different ways shouldn't be too much of a surprise, it's certainly recognised by the pharmaceutical industry and the medical profession. I bet there's a few members of this forum who've heard a GP say something like "let's try some of these and if they don't work . . . . . . . ".

    As for whether low cholesterol is what we want, cholesterol being vital for the normal functioning of the body, I'd be very cautious of somebody telling me what level it should be if they were paid by the pharmaceutical industry. British Heart Foundation research suggests that 5.4 is optimum. The graph is here on the forum somewhere.


    BTW, do you think that scientific research is more valuable than straw polls? You should investigate how pharmaceutical companies weed out test subjects before clinical trials.
     
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  17. Osidge

    Osidge Type 2 · Well-Known Member
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    It it is common on forums for the people who have problems to be vociferous in their pistings while those who have no problems and reduced cholesterol levels to say nothing. The number of people making adverse comments (not just on experience but on what they have read) versus the total population would be an interesting statistic. I have in my memory the issue of childhood vaccinations and autism. The "research" affected the decision making of many people but the research was not based on good data. In the research world we look for solid research that will give us answers or point us to further research.

    Doug
     
  18. Osidge

    Osidge Type 2 · Well-Known Member
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    I most certainly say that rigorous research is better than straw polls. I would not do research, be a research subject or spend time advising on diabetes and other research if I thought otherwise.

    Doug
     
  19. dannyw

    dannyw Type 1 · BANNED

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    And there's the problem....what solid research do you speak of ? For every one you highlight, there will be an opposing study.
     
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  20. Osidge

    Osidge Type 2 · Well-Known Member
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    There are conflicting pieces of research but that is often to do with the type of research - small study versus a very large prospective study or, indeed, research that looks at the combination of many research studies.
     
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