Kidney function Tests
Microalbumin/Creatinine
This test shows the number of albumin (protein) particles in the urine It is a test of kidney function. Protein in the urine is a warning sign. It may indicate kidney damage or disease or be an elevation due to an infection.
early morning urine sample ( but may be part of a 24 hour sample)
Microalbuminuria is defined as:
albumin:creatinine ratio >2.5mg/mmol (men) or >3.5mg/mmol (women)
or albumin concentration >20mg/l
Proteinuria is defined as:
albumin:creatinine ratio >30mg/mmol or albumin concentration >200mg/l
Estimated GFR: Estimated glomelurelar filtration raten ( AKA Creatinine clearance)
tests the efficiency of the kidneys
Creatinine is a substance that is mostly excreted (only tiny amounts are reabsorbed). When the kidneys aren't working as well as they should, creatinine builds up in the blood
Blood test according to info on web
(
though I'm also always asked for a small early morning urine sample at same time, I thought they used it so see how much was in the urine, now I'm unsure)
Creatinine in the blood sample range 60 - 120 µmol/L (adults) (my lab range)
EGFR is then calculated according to a formula for which your weight, gender and age are needed
see
http://www.nuh.nhs.uk/nch/antibiotics/Renal impairment/clcrcalc.asp
Normal Threshold value for renal insufficiency 60ml/mn
if there are other symptoms or specific problems this figure may be higher (kidney function can be reduced significantly before it becomes a problem so without other factors it is not diagnosed as chrionic kidney disease until below the 60ml/mn level)
If the person is Afro Carribean different thresholds apply.
Stage 1 >90 mL/min/1.73m²
Stage 2: 60 - 89 mL/min/1.73m²
Stage 3: 30 - 59 mL/min/1.73m²
Stage 4: 15 - 29 mL/min/1.73m²
Stage 5: <15mL/min/1.73m²
Creatinine clearance 24 hr urine sample + blood test ( done less nowadays, except in hospital)
(ranges vary beween labs)
70 - 140 mL/min (male)
70 - 125 mL/min (female
(they can also test protein/albumin in this but I haven't the ranges)
Other Blood Tests
Creatine kinase (CK), also known as
creatine phosphokinase (CPK)
This is a test of muscle damage and can be used to see if you have had a heart attack It is also used to see if there is muscle damage that could be attributed to statins It will be
very elevated)
Range from NHS site
40 - 215 U/L (male)
40 - 185 U/L (female)
Range ( my lab test results)
female < 145 male <170)
Exercise will also cause elevated results the doctor wasn’t concerned witha a result of 273 as I run several times a week,
( My last result was 273 but as I run several times a week the doc wasn’t worried)
Potassium
This tests the level of potassium (K) in blood.
Hyperkalaemia (too much) can be a problem with some drugs
• non-steroidal anti-inflammatory drugs (such as ibuprofen); beta-blockers (such as propanolol and atenolol), angiotensin-converting enzyme (ACE) inhibitors (such as captopril, enalapril, and lisinopril), and potassium-sparing diuretics (such as triamterene, amiloride, and spironolactone)., kidney problems
• DKA
Hypokalaemia (too little)
• can be a problem with some diuretic drugs
Range 3.5mmol/l-4.1mmo/l
This test may have to be repeated for out of range readings since factors like how the blood was drawn and storage effect the sample