- Messages
- 20
- Type of diabetes
- Type 1
- Treatment type
- Insulin
type1.5/LADA
- Thread starter jackie4617
- Start Date
phoenix
Expert
- Messages
- 5,671
- Type of diabetes
- Type 1
- Treatment type
- Pump
Type 1.5 isn't really an official classification. Sometimes it is used for LADA
Lada stands for latent onset autoimmune diabetes in adults.
It is a subset of T1 in that it is caused by an autoimmune attack on the beta cells. I some adults this takes place relatively slowly so the person doesn't require insulin to live in the early stages. Eventually though enough beta cells are destroyed that they need insulin to live (the time this takes varies )
Sometimes 1.5 it is used for people who have only a few antibodies and are perhaps nearer T2 (it gets complicated but I've just today read it used in this way)
'the very large group with what is often called “type 1.5” disease: that is, phenotypic type 2 disease with autoantibody positivity Type 1.5 diabetes is roughly two- to threefold more common than classic childhood-onset type 1 diabetes, but there is not as yet agreement on how to classify it. He excludes them from the type 1 diabetes category because type 1.5 patients have major problems with obesity and metabolic syndrome, which are not issues in managing type 1 disease or LADA' http://www.tudiabetes.org/forum/topics/dr-irl-hirsch-on-the-crisis-of
Sometimes it is used for people who have a genetic form of diabetes such as MODY (where it is caused by an inherited mutation) or Mitochondrial diabetes (again caused by a mutation, this time in the mitochondrial DNA)
People with MODY and mitochondrial diabetes sometimes require insulin but can sometimes control their diabetes with diet and exercise or certain drugs; it depends what specific problem the mutation in the DNA has caused
Lada stands for latent onset autoimmune diabetes in adults.
It is a subset of T1 in that it is caused by an autoimmune attack on the beta cells. I some adults this takes place relatively slowly so the person doesn't require insulin to live in the early stages. Eventually though enough beta cells are destroyed that they need insulin to live (the time this takes varies )
Sometimes 1.5 it is used for people who have only a few antibodies and are perhaps nearer T2 (it gets complicated but I've just today read it used in this way)
'the very large group with what is often called “type 1.5” disease: that is, phenotypic type 2 disease with autoantibody positivity Type 1.5 diabetes is roughly two- to threefold more common than classic childhood-onset type 1 diabetes, but there is not as yet agreement on how to classify it. He excludes them from the type 1 diabetes category because type 1.5 patients have major problems with obesity and metabolic syndrome, which are not issues in managing type 1 disease or LADA' http://www.tudiabetes.org/forum/topics/dr-irl-hirsch-on-the-crisis-of
Sometimes it is used for people who have a genetic form of diabetes such as MODY (where it is caused by an inherited mutation) or Mitochondrial diabetes (again caused by a mutation, this time in the mitochondrial DNA)
People with MODY and mitochondrial diabetes sometimes require insulin but can sometimes control their diabetes with diet and exercise or certain drugs; it depends what specific problem the mutation in the DNA has caused
- Messages
- 20
- Type of diabetes
- Type 1
- Treatment type
- Insulin
