1. Get the Diabetes Forum App for your phone - available on iOS and Android.
    Dismiss Notice
  2. Guest, we'd love to know what you think about the forum! Take the Diabetes Forum Survey 2021 »
    Dismiss Notice
  3. Diabetes Forum should not be used in an emergency and does not replace your healthcare professional relationship. Posts can be seen by the public.
    Dismiss Notice
  4. Guest, stay home, stay safe, save the NHS. Stay up to date with information about keeping yourself and people around you safe here and GOV.UK: Coronavirus (COVID-19). Think you have symptoms? NHS 111 service is available here.
    Dismiss Notice
Dismiss Notice
Find support, ask questions and share your experiences. Join the community »

Which basal insulin to ask for?

Discussion in 'Type 1 Diabetes' started by acron^, Jul 26, 2009.

  1. acron^

    acron^ · Well-Known Member

    Messages:
    143
    Likes Received:
    2
    Trophy Points:
    38
    So, I have an appointment with DN next week to talk about my low HbA1c. Whilst there I'm going to prompt for a change of regime. Premix is convenient but I don't feel like I can get the sort of control I truely need. There's a few horror stories about analogue insulins and side effects and some people seem to have more luck than others with this.

    As the title states, is there a particular basal or type that's considered better? I hear all this about human insulin, bovine insulin etc but I know very little about the differences. If anyone has any information on this, that'd also be greatly appreciated.
     
  2. fergus

    fergus Type 1 · Well-Known Member

    Messages:
    1,439
    Likes Received:
    131
    Trophy Points:
    83
    Hi acron,

    Comparison between the 2 main basal insulins is difficult as the evidence is largely anecdotal. From all the comments I've read I think Levemir seems to have fewer critics overall. A number of people have attributed a lack of stability in their control, some weight gain and other side effects to the Lantus they are taking and some seem to find these things improved on Levemir. Equally, there must be many Lantus users out there for whom it works very well. Who knows?
    I used Lantus until last year and had no apparent problem with it. Even so, I thought it might be worth trying Levemir for a while instead, just to see, so I started that in January.
    Overall I've found little difference. The doses are exactly the same, my blood sugars follow the same pattern, weight unchanged, and I don't really feel any different either. If anything, my hypo awareness may have improved a wee bit, but it's very hard to be completely objective about it.
    Equally, there are some who don't get on with the human insulins at all and have found significant benefits from using animal insulins, porcine or bovine, instead.
    It's a very personal thing really and I guess you should try what your HP recommends, but keep the alternatives in mind if you feel you need to change.

    All the best,

    fergus
     
  3. acron^

    acron^ · Well-Known Member

    Messages:
    143
    Likes Received:
    2
    Trophy Points:
    38
    Thanks fergus,

    With this in mind I'll push for Levemir (if I am given the choice) and I'll see if that meets agreement.
     
  4. janabelle

    janabelle · Well-Known Member

    Messages:
    816
    Likes Received:
    13
    Trophy Points:
    38
    Hi, Acron
    There are other long-acting insulins available besides Lantus and Levemir. Animal insulins have already been mentioned, but there are other synthetic insulins available including Insulatard, although a lot have been discontinued for no good reason.
    After 20 years as a type-1 and having tried different synthetic insulins over that time, I have to say that I've had the best control since changing on Pork Insulin just over a year ago. Lantus was the worst :twisted:
    Diabetes UK provide a booklet with ALL insulin and diabetes treatments listed. Give them a ring and they'll send you a copy. You can look at all the long-acting options and do your own research before seeing your doctor. Hope that helps
    Best of luck
    Jus
     
  5. WhimsicalWays

    WhimsicalWays · Active Member

    Messages:
    34
    Likes Received:
    3
    Trophy Points:
    28
    Hi there,

    Excuse my ignorance, but I am currently using Humulin NPH as my long-lasting insulin. I know many are transitioning off this, but it is working for me. Can anyone tell me the main advantages/difference between NPH versus Levemir/Lantus.

    Thank you!
     
  6. janabelle

    janabelle · Well-Known Member

    Messages:
    816
    Likes Received:
    13
    Trophy Points:
    38
    Hi, I would say,and evidence suggests that there are no advantages in changing to Lantus/Levemir from NPH. Of course medics will tell you otherwise, but just read the amount of postings on this forum from people having problems on Lantus and Levemir, It is not the best option.

    My advice would be stick with a long-acting NPH or try animal insulin. You DO have a choice, and should not be pressured by your doctor into taking analogue insulin. I was told,while on Insulatard, that Lantus would give me good control. Instead it destroyed 4 1/2 valuable years of my life, and that is no exaggeration.

    Lantus and Levemir clinical studies only lasted 28 weeks maximum for type-1. These insulins are not proven safe in pregnancy or for young children, as they were only tested on rabbits and mice, and both companies state they should only be used in pregnancy "if clearly needed". The info is available on the Sanofi Aventis & Novo Nordisk websites, and is a bit of an eye opener, and a worry.

    GM in relation to food has become a dirty word. Perhaps if the term "GM insulin" were used for these insulins, instead of the misleading terms "Human Insulin" and '"insulin", which they are not, people would think twice about taking them, and be better for it!

    You've asked the question "which basal insulin to ask for?". I can't tell you what insulin to take,but from my experience Hyprurin Porcine Isophane is superior -with it I have the best control I've ever had in 20 years as a type-1.
    Jus
     
  7. latecomer

    latecomer · Member

    Messages:
    16
    Likes Received:
    0
    Trophy Points:
    41
    I have just been doing some research on the internet about Lantus, which I use and came across this has anyone else seen or heard of this?
    http://www.diabetologia-journal.org/cancer.html
    Also brilliant site that my Nurse put me onto
    http://www.iddtinternational.org
    have a look please
     
  8. acron^

    acron^ · Well-Known Member

    Messages:
    143
    Likes Received:
    2
    Trophy Points:
    38
    This is really interesting stuff folks! Thanks a lot :)
     
  • Meet the Community

    Find support, connect with others, ask questions and share your experiences with people with diabetes, their carers and family.

    Did you know: 7 out of 10 people improve their understanding of diabetes within 6 months of being a Diabetes Forum member. Get the Diabetes Forum App and stay connected on iOS and Android

    Grab the app!
  • Tweet with us

  • Like us on Facebook