Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age

January 15, 2014

Richard H Tuligenga et al. The Lancet Diabetes & Endocrinology. Doi: 10.1016/S2213-8587(13)70192-X

In this study 5,653 participants from the Whitehall II cohort study were classified into four groups: normoglycaemia, prediabetes, newly diagnosed diabetes, and known diabetes.

Tests of memory, reasoning, phonemic and semantic fluency, and a global score that combined all cognitive tests, were assessed three times over 10 years.

It was found that the risk of accelerated cognitive decline in middle-aged patients with type 2 diabetes is dependent on both disease duration and glycaemic control.

Article information
The Lancet Diabetes & Endocrinology
Jan 15, 2014
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