New study reveals diabetes secrets

Thu, 04 Jan 2007
Fresh research published in the Journal of Clinical Investigation indicates that altering blood glucose levels could have a major influence on the prevention of type 2 diabetes at an early stage.

Type 2 will often occur when cells within the body stops responding to insulin, an integral hormone that lowers blood glucose levels within the body. Before people become diabetic, their body overcompensates for insulin resistance by increasing beta cells in the pancreas.

A new study at the University of Japan indicates that changing glucose concentration triggers beta cell volumes and mass. They found a particular molecule, Insulin Receptor Substrate 2 (IRS2), which mediates beta cell mass. The team also investigated mice with a single copy of a gene called GCK.

The researchers hoped that future exploration would reveal new strategies of increasing beta cell mass to treat type 2 diabetes.
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