New endo report says weight-setting is our most powerful tool to avoid disease

A new statement, published by the Endocrine Society, suggests that an early weight ‘reset’ is perhaps the most effective tool at our disposal to prevent metabolic issues leading to type 2 diabetes.
The authors of the findings, published in Endocrine Reviews, question why some authorities have raised upward the defended or acceptable level of body fat when all the evidence points to problems linked to excess weight.
The issue was actually brought up by British scientists recently, who released data that very strongly discredit myths around the so-called ‘metabolically healthy’ obesity phenotype.
It was considered a well-needed reality check, as these scientists felt that, awash in misinformation, some were almost starting to condone having a high body mass index (BMI), while others even looked at it as an advantage.
In their report, the Endocrine Society hints that we have to look at evolutionary physiology to understand the mechanisms we’re predisposed to that conserve body fat as a survival aid.
They remind us that at a fundamental level, obesity generally develops as a coping mechanism after years of self-abuse, often involving an unbalanced, hypercaloric diet and too little activity.
There is also this still very much unexplained for phenomenon whereby the body seems to adapt to any calorie deficit very quickly, making it hard to keep the weight off with the same level of effort thereafter.
In addition to that, the report reiterates the importance of having, for example, an isocaloric diet lower in refined sugar and carbs, and other variables, like sleep and stress, dialed in to reduce obesity risks.
A recent genetic study, in support of these findings, detailed the causal effect of a high BMI on heart and diabetes risks.
It shows that gene variations linked to a high BMI are associated with a 2.5 times greater risk of developing type 2 diabetes, over one and a half times more hypertension and more heart disease.
It argues, just like the Endocrine Society, that more work needs to be done to examine how obesity is affected by genetics, the gut microbiomen, bariatric surgery and brain signals. Those are the grand themes around obesity that are being heavily debated at the moment within the medical community.