I accompanied my friend yesterday at her endocrinologist's visit. She couldn't tolerate Metformin and he switched her to Glumetza, an alternative to Metformin. She said this morning that she had not side effects at all, no upset stomach, no diarrhea etc.
"Although other long-acting forms of metformin are available (such as Glucophage XR® and Fortamet®), Glumetza is not equivalent to these products. Glumetza is specially designed to release the medication in the stomach, not in the intestines (as with other metformin products). This may decrease the intestinal-related side effects (such as diarrhea and gas).
Who Makes It?
Glumetza is manufactured by Depomed, Inc.
How Does Glumetza Work?
Glumetza is part of a class of diabetes medications known as biguanide medications. Glumetza works in several ways. It decreases the amount of sugar (glucose) made by the liver. It can also decrease the amount of sugar absorbed into the body from the diet and can make insulin receptors more sensitive, helping the body respond to its own insulin better. All of these effects cause a decrease in blood sugar levels and lead to better control of diabetes.
Because Glumetza does not increase the amount of insulin produced by the body, it is less likely to cause dangerously low blood sugar (hypoglycemia), like many other diabetes medications can."