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<blockquote data-quote="GrantGam" data-source="post: 1568873" data-attributes="member: 295621"><p>I'll start by saying that I'm not overly surprised that you're having issues. As a T1, routine and consistency seems to be critical for the majority of other T1's I've spoken with. The fundamental constant, in my opinion, for stable BG's is a regular and steady daily carb intake. It may be 50g or 500g, but I've always found difficulties if I've suddenly changed this value.</p><p></p><p>The DIA of most rapid insulin is 3-5 hours, so even in your fasting periods, you may well have active insulin on-board. If you've taken too much insulin (ie, not factored in your IOB) then you could see drops between meals. Exactly when these drops happen - is usually an individual thing, and does depend on what you've eaten and when. If you're eating more than 3 times per day, insulin stacking can happen and that may be a reason for your BG's dropping between meals.</p><p></p><p>Also, even if you think your ICR's are set correctly, the higher your carb intake - the larger your error margin can become. For instance, if you ate 100g of carbs and used an ICR of 1:10, when in fact you are 1:12 - that would be 1.6u extra insulin administered. 1.6u can drop BG by as much, and possibly even more than 5mmol/L. So as you can see, hypos are easily encountered when I:C ratios aren't quite right.</p><p></p><p>Have you tested for ketones on your 50g carb days? If you're in dietary ketosis during these days, then when you swap to high carb days, your liver may rob a lot of the glucose from your blood stream to replenish glycogen stores. It's a possibility.</p><p></p><p>Apologies for the long winded reply, but as you can appreciate - there are loads of reasons why you may be experiencing these hypos when reintroducing carbs.</p></blockquote><p></p>
[QUOTE="GrantGam, post: 1568873, member: 295621"] I'll start by saying that I'm not overly surprised that you're having issues. As a T1, routine and consistency seems to be critical for the majority of other T1's I've spoken with. The fundamental constant, in my opinion, for stable BG's is a regular and steady daily carb intake. It may be 50g or 500g, but I've always found difficulties if I've suddenly changed this value. The DIA of most rapid insulin is 3-5 hours, so even in your fasting periods, you may well have active insulin on-board. If you've taken too much insulin (ie, not factored in your IOB) then you could see drops between meals. Exactly when these drops happen - is usually an individual thing, and does depend on what you've eaten and when. If you're eating more than 3 times per day, insulin stacking can happen and that may be a reason for your BG's dropping between meals. Also, even if you think your ICR's are set correctly, the higher your carb intake - the larger your error margin can become. For instance, if you ate 100g of carbs and used an ICR of 1:10, when in fact you are 1:12 - that would be 1.6u extra insulin administered. 1.6u can drop BG by as much, and possibly even more than 5mmol/L. So as you can see, hypos are easily encountered when I:C ratios aren't quite right. Have you tested for ketones on your 50g carb days? If you're in dietary ketosis during these days, then when you swap to high carb days, your liver may rob a lot of the glucose from your blood stream to replenish glycogen stores. It's a possibility. Apologies for the long winded reply, but as you can appreciate - there are loads of reasons why you may be experiencing these hypos when reintroducing carbs. [/QUOTE]
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