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<blockquote data-quote="Oldvatr" data-source="post: 1608317" data-attributes="member: 196898"><p>Here is some food for thought:</p><p><a href="http://www.diabetesincontrol.com/glycosylation/" target="_blank">http://www.diabetesincontrol.com/glycosylation/</a></p><p></p><p>Although it does not really discuss peaks and troughs in bgl levels, it seems that the effect of short spikes has almost zero effect on HbA1c. There is a discussion on possible harmful pathways, and how thesw might be mitigated, but again they are discussed long term, and short term effects due to peaks is not discussed. Interesting comments about Vit C and ALA but this is only commentary and may be POV not fact. The article reads like a blog, so not to be taken as gospel</p><p></p><p>Interesting comment in the article seems to imply that proteins also get glycated, and this reduces their effectiveness directly eg in skin and collagen, leading to AGE by products. Again the article does not give timings for that process to occur. There is an article describing AGE products and their kinectivity, but is it an article that needs a degree in biology to understand and is way above my paygrade so I am not linking to it here.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 1608317, member: 196898"] Here is some food for thought: [URL]http://www.diabetesincontrol.com/glycosylation/[/URL] Although it does not really discuss peaks and troughs in bgl levels, it seems that the effect of short spikes has almost zero effect on HbA1c. There is a discussion on possible harmful pathways, and how thesw might be mitigated, but again they are discussed long term, and short term effects due to peaks is not discussed. Interesting comments about Vit C and ALA but this is only commentary and may be POV not fact. The article reads like a blog, so not to be taken as gospel Interesting comment in the article seems to imply that proteins also get glycated, and this reduces their effectiveness directly eg in skin and collagen, leading to AGE by products. Again the article does not give timings for that process to occur. There is an article describing AGE products and their kinectivity, but is it an article that needs a degree in biology to understand and is way above my paygrade so I am not linking to it here. [/QUOTE]
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