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<blockquote data-quote="kokhongw" data-source="post: 1311887" data-attributes="member: 277199"><p>I would be cautious about advocating sugar substitutes...some factors observed to cause hyperinsulinemia...</p><p>“Hyperinsulinemia: Cause or Consequence?” </p><p><a href="http://diabetes.diabetesjournals.org/content/61/1/4" target="_blank">http://diabetes.diabetesjournals.org/content/61/1/4</a></p><p></p><p>"Several additional nonlipid stimuli were also identified in our screening, including artificial sweeteners and iron.Artificial sweeteners that are also frequently present in modern foods were found to impact insulin secretion.Shown here is insulin secretion at basal and two stimulatory concentrations of glucose in response to saccharin,aspartame, and sucralose. All stimulated basal secretion acutely, but saccharin was most potent and also inhibited glucose-stimulated secretion. Interestingly,only saccharin stimulated basal secretion at concentrations that might be achieved by high levels of consumption,for example,in diet beverages."</p></blockquote><p></p>
[QUOTE="kokhongw, post: 1311887, member: 277199"] I would be cautious about advocating sugar substitutes...some factors observed to cause hyperinsulinemia... “Hyperinsulinemia: Cause or Consequence?” [URL]http://diabetes.diabetesjournals.org/content/61/1/4[/URL] "Several additional nonlipid stimuli were also identified in our screening, including artificial sweeteners and iron.Artificial sweeteners that are also frequently present in modern foods were found to impact insulin secretion.Shown here is insulin secretion at basal and two stimulatory concentrations of glucose in response to saccharin,aspartame, and sucralose. All stimulated basal secretion acutely, but saccharin was most potent and also inhibited glucose-stimulated secretion. Interestingly,only saccharin stimulated basal secretion at concentrations that might be achieved by high levels of consumption,for example,in diet beverages." [/QUOTE]
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