Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Type 1.5/LADA Diabetes
Help! Type 1/Lada or Type 2
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="phoenix" data-source="post: 264592" data-attributes="member: 12578"><p>GAD antibodies are not necessarily definitive. There are people without diabetes that have them and they are also present as a marker in at least one other condition(stiff person syndrome).</p><p> I understand that higher amounts of antibodies are more indicative of an early progression to insulin and hence LADA.(unfortunately try as I can, I haven't found how many these amount to in the units that are used in the UK... research papers use at least 3 different units in research papers and I understand that that there are different methods of analysis and ranges). </p><p></p><p>In one big study there were 1870 subjects diagnosed with T2, of these 168 had GAD antibodies. After 6 years, over 50% of those with antibodies (90) had needed to be put onto insulin but so did 147 of those without antibodies. The other 87 with antibodies hadn't needed to go onto insulin at this point. We don't know how many of these eventually needed insulin but they were following a progression more typical of T2.</p><p></p><p>Having said all that, your husband reminds me of those people far more of those that I have read about who eventually end up diagnosed as slow onset T1/LADA rather than T2.</p><p></p><p>I agree with Pauls suggestion of documenting everything and eating a healthy diet. Test as frequently as you can and make sure that you have some ketone strips. If blood glucose levels reach the high teens/twenties and there are ketones present, then it becomes an emergency.</p><p></p><p> I totally understand the problems about using service medical centres (been there for many years, until they decided to get rid of dependants to the local GPS, ) One consideration though is that they may be wary of introducing insulin since it might have big implications for his career. </p><p>.</p></blockquote><p></p>
[QUOTE="phoenix, post: 264592, member: 12578"] GAD antibodies are not necessarily definitive. There are people without diabetes that have them and they are also present as a marker in at least one other condition(stiff person syndrome). I understand that higher amounts of antibodies are more indicative of an early progression to insulin and hence LADA.(unfortunately try as I can, I haven't found how many these amount to in the units that are used in the UK... research papers use at least 3 different units in research papers and I understand that that there are different methods of analysis and ranges). In one big study there were 1870 subjects diagnosed with T2, of these 168 had GAD antibodies. After 6 years, over 50% of those with antibodies (90) had needed to be put onto insulin but so did 147 of those without antibodies. The other 87 with antibodies hadn't needed to go onto insulin at this point. We don't know how many of these eventually needed insulin but they were following a progression more typical of T2. Having said all that, your husband reminds me of those people far more of those that I have read about who eventually end up diagnosed as slow onset T1/LADA rather than T2. I agree with Pauls suggestion of documenting everything and eating a healthy diet. Test as frequently as you can and make sure that you have some ketone strips. If blood glucose levels reach the high teens/twenties and there are ketones present, then it becomes an emergency. I totally understand the problems about using service medical centres (been there for many years, until they decided to get rid of dependants to the local GPS, ) One consideration though is that they may be wary of introducing insulin since it might have big implications for his career. . [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Type 1.5/LADA Diabetes
Help! Type 1/Lada or Type 2
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…