Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Ask A Question
How should blood glucose levels raise and fall to glucose?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="phoenix" data-source="post: 623879" data-attributes="member: 12578"><p>The research that's referred to by Jenny Ruhl in her take on what are normal levels came from a lecture but the final research was published here</p><p><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/?report=reader#!po=52.7778" target="_blank">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/?report=reader#!po=52.7778</a></p><p>. Fig 2 shows a representative profile (much like the one on her site)</p><p> </p><p>However, in this paper there are also representative profiles for glucose levels after 4 different meals (ie fast and slow absorbing meals)</p><p>meal composition table 1 (all had around 50g carbs, fat, protein and fibre was different )</p><p> </p><p> </p><p>The profiles show differing characteristics (fig 5)</p><p>eg:</p><p>A meal with kidney beans, wholemeal bread, cheese and salami had a relatively flat profile,</p><p>A meal with , toast, jam, curd cheese and orange juice had a much higher spike.</p><p> </p><p>The time to peak glucose varied between meals and a lot between subjects. (table 4)</p><p>eg:</p><p>The average time to peak for the kidney bean meal was 57 min but this was+/- 24 min</p><p>By contrast a meal with rice pudding, sugar and cinnamon had an average time to peak of only 43 min , +/- 10.8min</p><p> </p><p>That particular study had quite young subjects and just a few days.of monitoring</p><p><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/" target="_blank">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/</a></p><p> </p><p>When they were doing the research on how HbA1cs reflected average blood glucose, they also did a lot of continuous monitoring of normal subjects. with subjects wearing the device for an average (median) of 230hours so much longer than in the study above. These were also wider group of people from various countries, with an older average age of 41. . They defined normal as having no history of diabetes, a fasting glucose of below5.4mmol/l and an HbA1c of below 6.5%</p><p>Unfortunately they do not report similar profile graphs. What they describe are the periods of time spent above various cut off points.</p><p>[ATTACH=full]6866[/ATTACH]</p><p> </p><p>There were 8 people who spent longer than 2 hours a day above 7.8mmo/l. They were older (average age 55), 6 out of 8 were women, 6 out of 8 were non white, they had a BMI above 29 and an average HbA1c of 5.7% and fasting glucose of 6.1 mmol/l There were 3 people who spent 5 hours a day above 7.8mmol/l . These had an HbA1c of 5.4-5.% percent</p><p> </p><p>If you look at the discussion section you will see they say that they say it is possible that some of the people could have had impaired fasting glucose but also that in general the average HbA1c was well below a diabetes cut off level. They also say that the general pattern reflects that found in other studies and gives some figures for them.</p><p>(the other studies are behind pay walls )</p><p><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892065/" target="_blank">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892065/</a></p><p> </p><p> </p><p>The studies together seem to show that most spend some time over 7.8mmol/l . The first shows that the time to peak glucose varies, even in these young people between individuals and the type of meals eaten. The peak seems to be probably somewhere between 45mi and 95min. How long it stays up again depends on the meal and the individual response. The younger people in the first study were at higher levels for less time than older people in the second.</p></blockquote><p></p>
[QUOTE="phoenix, post: 623879, member: 12578"] The research that's referred to by Jenny Ruhl in her take on what are normal levels came from a lecture but the final research was published here [url]http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/?report=reader#!po=52.7778[/url] . Fig 2 shows a representative profile (much like the one on her site) However, in this paper there are also representative profiles for glucose levels after 4 different meals (ie fast and slow absorbing meals) meal composition table 1 (all had around 50g carbs, fat, protein and fibre was different ) The profiles show differing characteristics (fig 5) eg: A meal with kidney beans, wholemeal bread, cheese and salami had a relatively flat profile, A meal with , toast, jam, curd cheese and orange juice had a much higher spike. The time to peak glucose varied between meals and a lot between subjects. (table 4) eg: The average time to peak for the kidney bean meal was 57 min but this was+/- 24 min By contrast a meal with rice pudding, sugar and cinnamon had an average time to peak of only 43 min , +/- 10.8min That particular study had quite young subjects and just a few days.of monitoring [url]http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/[/url] When they were doing the research on how HbA1cs reflected average blood glucose, they also did a lot of continuous monitoring of normal subjects. with subjects wearing the device for an average (median) of 230hours so much longer than in the study above. These were also wider group of people from various countries, with an older average age of 41. . They defined normal as having no history of diabetes, a fasting glucose of below5.4mmol/l and an HbA1c of below 6.5% Unfortunately they do not report similar profile graphs. What they describe are the periods of time spent above various cut off points. [ATTACH=full]6866[/ATTACH] There were 8 people who spent longer than 2 hours a day above 7.8mmo/l. They were older (average age 55), 6 out of 8 were women, 6 out of 8 were non white, they had a BMI above 29 and an average HbA1c of 5.7% and fasting glucose of 6.1 mmol/l There were 3 people who spent 5 hours a day above 7.8mmol/l . These had an HbA1c of 5.4-5.% percent If you look at the discussion section you will see they say that they say it is possible that some of the people could have had impaired fasting glucose but also that in general the average HbA1c was well below a diabetes cut off level. They also say that the general pattern reflects that found in other studies and gives some figures for them. (the other studies are behind pay walls ) [url]http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892065/[/url] The studies together seem to show that most spend some time over 7.8mmol/l . The first shows that the time to peak glucose varies, even in these young people between individuals and the type of meals eaten. The peak seems to be probably somewhere between 45mi and 95min. How long it stays up again depends on the meal and the individual response. The younger people in the first study were at higher levels for less time than older people in the second. [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Ask A Question
How should blood glucose levels raise and fall to glucose?
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…