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<blockquote data-quote="Foggitthedoggit" data-source="post: 117636" data-attributes="member: 24337"><p>Perhaps some might wish to consider the methodology behind a longitudinal study.</p><p></p><p>With regard to the comment made in an earlier post::</p><p></p><p>“Why should a low HbA1c in itself be dangerous?” </p><p></p><p>I don't think that the study is saying that at all. To me all that it is saying is that x patients were included in a longitudinal study and the known outcomes in terms of death were..... In simple terms someone put x into the sausage machine and what was observed coming out was y; that is, of the x patients involved, bearing in mind the associated patient medical data, the 'best survivors' (but ultimately deceased anyway) were those with an HbA1c at about 7.5 per cent. The study recognises that high HbA1cs are 'bad' and increase risk of death (and I suppose many on this forum would all 'intuitively' surmise that outcome - given the possible complications). The 'but' is the surprise that those with 'normal' (whatever that is) HbA1cs that many on this forum and elsewhere undoubtedly propound we should all strive towards, appear also to carry an increased risk of death earlier than those who have marginally less stringent controls. </p><p></p><p>The fact that 'normal' people do not appear to be dropping off like flies is neither here nor there. Diabetes, whether we like it or not, is associated to an increased risk of heart and stroke problems (and for some losing their feet), which make us all more vulnerable to an earlier that desired demise. </p><p></p><p>To me the article suggests that, for those of us who do manage tight control, don't be over zealous it might be counter-productive. For the bad guy's its 'well that's would we said'. And for the relaxed – live it and give it the best. </p><p></p><p>Need to re-think about my recent HbA1c of 5.6. </p><p></p><p>As for the initial reference to low carb it must be said that many of that ilk would have it that that is the way to achieving 'normal' HbA1cs.</p></blockquote><p></p>
[QUOTE="Foggitthedoggit, post: 117636, member: 24337"] Perhaps some might wish to consider the methodology behind a longitudinal study. With regard to the comment made in an earlier post:: “Why should a low HbA1c in itself be dangerous?” I don't think that the study is saying that at all. To me all that it is saying is that x patients were included in a longitudinal study and the known outcomes in terms of death were..... In simple terms someone put x into the sausage machine and what was observed coming out was y; that is, of the x patients involved, bearing in mind the associated patient medical data, the 'best survivors' (but ultimately deceased anyway) were those with an HbA1c at about 7.5 per cent. The study recognises that high HbA1cs are 'bad' and increase risk of death (and I suppose many on this forum would all 'intuitively' surmise that outcome - given the possible complications). The 'but' is the surprise that those with 'normal' (whatever that is) HbA1cs that many on this forum and elsewhere undoubtedly propound we should all strive towards, appear also to carry an increased risk of death earlier than those who have marginally less stringent controls. The fact that 'normal' people do not appear to be dropping off like flies is neither here nor there. Diabetes, whether we like it or not, is associated to an increased risk of heart and stroke problems (and for some losing their feet), which make us all more vulnerable to an earlier that desired demise. To me the article suggests that, for those of us who do manage tight control, don't be over zealous it might be counter-productive. For the bad guy's its 'well that's would we said'. And for the relaxed – live it and give it the best. Need to re-think about my recent HbA1c of 5.6. As for the initial reference to low carb it must be said that many of that ilk would have it that that is the way to achieving 'normal' HbA1cs. [/QUOTE]
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