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Type 1 Diabetes
Insulin duration Vs BS reduction
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<blockquote data-quote="tim2000s" data-source="post: 1329544" data-attributes="member: 30007"><p>It's interesting. At 0.3U/kg, we see total duration of about 10 hours. At 0.15U/kg it's about 6 hours. I guess if you are using less, then it would be shorter still.</p><p></p><p>A study of 25 men in 1998 showed that at 0.1U/kg, the insulin Aspart was out of the system in around 4 hours. If you dig even further, you'll find that dependent on site, the absorption profiles differ again, with abdomen being much faster than other sites. </p><p></p><p>So while it's rather hit and miss, it seems that dosage is the best indicator of how long insulin remains in the body, which makes sense given the physiological mechanisms for the use and breakdown of insulin.</p></blockquote><p></p>
[QUOTE="tim2000s, post: 1329544, member: 30007"] It's interesting. At 0.3U/kg, we see total duration of about 10 hours. At 0.15U/kg it's about 6 hours. I guess if you are using less, then it would be shorter still. A study of 25 men in 1998 showed that at 0.1U/kg, the insulin Aspart was out of the system in around 4 hours. If you dig even further, you'll find that dependent on site, the absorption profiles differ again, with abdomen being much faster than other sites. So while it's rather hit and miss, it seems that dosage is the best indicator of how long insulin remains in the body, which makes sense given the physiological mechanisms for the use and breakdown of insulin. [/QUOTE]
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