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Diabetes Discussion
Type 1.5/LADA Diabetes
LADA vs. Type 1?
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<blockquote data-quote="MangosteenElbow" data-source="post: 1474237" data-attributes="member: 322425"><p>Very much agree with the previous post.</p><p>The biomarkers for Type 1.5 differ from those for Type 1. </p><p>This means the diagnosis can be different before onset, at onset, under medication and under insulin therapy.</p><p>I have seen the good work on relevant biomarkers published only in the last 18 months or so. Before then it was mostly hypothesis and exploration (even going back to 60s, 70s and 80s).</p><p>The first challenge is to resilve the differences that matter. That us not a simple issue.</p><p>The next challenge is to cinsidet long term therapies that effectively and measurably work on the things that generate testable biomarkers.</p><p>Then there is the challenge of framing so that GPs and endos can manage it.</p><p>When i went through those early days / years after late onset it was clearly too hard and if only of vague interest even to the venerable experts.</p><p>Now i know better what blood tests to order. Different focus from that for classic type 1.</p></blockquote><p></p>
[QUOTE="MangosteenElbow, post: 1474237, member: 322425"] Very much agree with the previous post. The biomarkers for Type 1.5 differ from those for Type 1. This means the diagnosis can be different before onset, at onset, under medication and under insulin therapy. I have seen the good work on relevant biomarkers published only in the last 18 months or so. Before then it was mostly hypothesis and exploration (even going back to 60s, 70s and 80s). The first challenge is to resilve the differences that matter. That us not a simple issue. The next challenge is to cinsidet long term therapies that effectively and measurably work on the things that generate testable biomarkers. Then there is the challenge of framing so that GPs and endos can manage it. When i went through those early days / years after late onset it was clearly too hard and if only of vague interest even to the venerable experts. Now i know better what blood tests to order. Different focus from that for classic type 1. [/QUOTE]
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