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Diabetes Management
Diabetes Medication and Drugs
Metformin/Biguanides
Metformin SR side effects
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<blockquote data-quote="Celeriac" data-source="post: 933068" data-attributes="member: 188243"><p>I was given Metformin and I had severe diarrhoea and felt terrible. Loperamide had no effect whatsoever. Had temper tantrum on the phone with GP and he prescribed SR. </p><p></p><p>I take morning and evening. I don't have problems with SR tolerance now. However if I'm very late taking tablets or miss them (travel delays) I get diarrhoea unless I take 2 loperamide as soon as poss, then just carry on with next dose. My theory is that the loperamide just slows digestion down a bit and pre-empts the diarrhoea. Obviously, that would be no good for anyone with gastroparesis and I'm not suggesting that anyone should pop loperamide, it just works for me. </p><p></p><p>I try very hard to make sure that I don't miss tablets or take very late though !</p></blockquote><p></p>
[QUOTE="Celeriac, post: 933068, member: 188243"] I was given Metformin and I had severe diarrhoea and felt terrible. Loperamide had no effect whatsoever. Had temper tantrum on the phone with GP and he prescribed SR. I take morning and evening. I don't have problems with SR tolerance now. However if I'm very late taking tablets or miss them (travel delays) I get diarrhoea unless I take 2 loperamide as soon as poss, then just carry on with next dose. My theory is that the loperamide just slows digestion down a bit and pre-empts the diarrhoea. Obviously, that would be no good for anyone with gastroparesis and I'm not suggesting that anyone should pop loperamide, it just works for me. I try very hard to make sure that I don't miss tablets or take very late though ! [/QUOTE]
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